Northwestern University Feinberg School of Medicine

Center for Circadian and Sleep Medicine

Clinical Trials

The Center for Circadian and Sleep Medicine is focused on clinical research. Learn more about the trials and participation opportunities via the search results for Northwestern Neurology on clinicaltrials.gov. Below is a selected list of our current active protocols.

Feinberg Clinical Trials

Scientists at the medical school are conducting hundreds of clinical trials daily. Learn more about all our work via the Feinberg Office of Research Clinical Trials page. Search for trials by disease or condition.

Northwestern University

CoordinatorPIStudy Description
Alexandra Ritger
sleeplab( at )northwestern.edu
312-503-0018
Phyllis C. Zee, MD, PhD

MNEMONIC Sound and Memory Study - Sleep, particularly deep sleep, is important for memory. Sleep deprivation can lead to difficulty with attention and memory performance. Enhancing deep sleep with medications has had limited success. We have recently developed a new approach to increase deep sleep by delivering sound waves played through headphones in a specific sequence during sleep in healthy people. When applied during sleep the sound waves increase deep sleep. The goal of this study is to determine the ability of auditory stimulation with these sound waves to improve memory performance.  Learn more by vising our Current Research Project page.

Rosemary Ortiz
r-ortiz( at )northwestern.edu
312-908-1024
Phyllis C. Zee, MD, PhDSleep and Metabolic Disturbance - Our overarching goal is to develop treatments to improve sleep quality and depth and also reduce cardiovascular risk. This study is a randomized sham-controlled parallel group pilot trial of acoustic stimulation in people with metabolic syndrome (obesity, hypertension, diabetes). Find details about this study via our Current Research Project page.
Alexandra Ritger
sleeplab( at )northwestern.edu
312-503-0018
Phyllis C. Zee, MD, PhDHuman Timestamp: Traumatic Brain Injury - The purpose of this study is to develop a diagnostic test for individuals with disorders of circadian timing. We will evaluate the change in gene expression and metabolite profiles over the 24 hour period to determine whether changes to the internal clock can predict recovery from traumatic brain injury. Individuals who have been diagnosed with a mild traumatic brain injury within the past year are encouraged to participate.  Learn more by vising our Current Research Project page.
Christine Smith, MA
Christine.Smith( at )northwestern.edu
312-503-6628
Jason C. Ong, PhDThe MATRICS Study - This study aims to investigate the effectiveness of different combinations and sequences of evidence-based treatment strategies for people with both Obstructive Sleep Apnea and Insomnia. Participants will be randomly assigned to one of three treatment conditions using a medical device known as CPAP, or using this device in combination with a behavioral treatment to improve sleep.