Northwestern University Feinberg School of Medicine

Department of Cell & Molecular Biology

Neuroscience and Alzheimer's

Neurons are extremely interesting cells because genetic information and most of the synthetic machinery is located in one region of the cell, and materials must be transported long distances (sometimes up to one meter) to supply the axon terminus. Disruption of this transport and alterations in the structural proteins often lead to protein aggregation and intracellular inclusions associated with neurodegenerative diseases. Neurobiologists within the department are working to decipher why these cellular disruptions occur, and how they lead to disease.

A major focus is on Alzheimer’s Disease, with studies aimed at developing an understanding of:

Labs in this Research Area