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Colum MacKinnon, PhD  
Associate Chair, Research
Assistant Professor, NUPTHMS
Faculty, Northwestern University Institute for Neuroscience, The Graduate School, Department of Neurology
c-mackinnon@northwestern.edu

Education

PhD Physiology (neuroscience), University of Toronto, Canada
Postdoctoral training, Human Movement and Balance Unit, Institute of Neurology, London, UK, sensorimotor neurophysiology
MS Kinesiology (biomechanics), University of Waterloo, Canada
BS Kinesiology, University of Waterloo, Canada

Teaching Interests

Neuroscience, kinesiology, physiology

Research Interests

Cortical control of movement preparation and initiation in healthy adults and basal ganglia disorders

Professional Activities

Society for Neuroscience, Movement Disorders Society

Representative Publications

Lewis, G.N., MacKinnon, C.D., Perreault, E.J.  (2006)  The effect of task instruction on spinal and supraspinal reflex pathway excitability in the biceps muscle.  Experimental Brain Research.  174(3): 413-425.

Prodoehl, J., MacKinnon, C.D., Comella, C.L., Corcos, D.M.  (2006)  Rate of force production and relaxation is impaired in patients with focal hand dystonia.  Parkinsons Disease and Related Disorders. 12(6): 363-371.

Prodoehl, J., MacKinnon, C.D., Comella, C.L., Corcos, D.M.  (2006)  Strength deficits in primary focal arm dystonia.  Movement Disorders.  21(1): 18-27.

MacKinnon, C.D., Gilley, E.A., Weis-McNulty, A., Simuni, T.  (2005)  Pathways mediating abnormal intracortical inhibition in Parkinson’s disease.  Annals of Neurology.  58(4): 516-524.

MacKinnon, C.D., Webb, R.M., Silberstein, P., Tisch, S., Asselman, P., Limousin, P., Rothwell, J.C.  (2005)  Stimulation through electrodes implanted near the subthalamic nucleus activates projections to motor areas of cerebral cortex in patient's with Parkinson's disease.  European Journal of Neuroscience.  21(5):1394-1402.

Lewis, G.N., Perreault, E.J., MacKinnon, C.D.  (2005)  The influence of perturbation duration and velocity on the long-latency response to stretch in the biceps muscle.  Experimental Brain Research.  163(3):361-369.

MacKinnon, C.D., Quartarone, A., Meyer, B.U., Fung, V.S., Rothwell, J.C. (2004)  Interhemispheric asymmetry of ipsilateral corticofugal projections to proximal muscles in humans.  Experimental Brain Research. 157(2): 225-233.

MacKinnon, C.D., Velickovic, M., Drafta, C., Hesquijarosa, A., Brin, M.F. (2004) Corticospinal excitability accompanying ballistic wrist movements in primary dystonia.  Movement Disorders. 19(3): 273-284.

Rothwell, J.C., MacKinnon, C.D., Valls-Solé, J.  (2002)  Role of brainstem-spinal projections in voluntary movement.  Movement Disorders.  17(2), Suppl. 2: S27-S29.

Modugno, N., Nakamura, Y., MacKinnon, C.D., Filipovic, S.R., Bestmann, S., Berardelli, A., Rothwell, J.C.  (2001)  Motor cortex excitability following short trains of repetitive magnetic stimuli.  Experimental Brain Research.  140(4): 453-459.

Münchau, A., Schrag, A., Chuang, C., MacKinnon, C.D., Bhatia, K.P., Quinn, N.P., Rothwell, J.C.  (2001)  Arm tremor in cervical dystonia differs from essential tremor and can be classified by onset age and spread of symptoms.  Brain.  124(9): 1765-1776.

MacKinnon, C.D., Rothwell, J.C.  (2000)  Time-varying changes in corticospinal excitability accompanying the triphasic EMG pattern in humans.  Journal of Physiology.  528(3): 633-645.

MacKinnon, C.D., Verrier, M.C., Tatton, W.G.  (2000)  Motor cortical potentials precede long-latency EMG activity evoked by imposed displacements of the human wrist.  Experimental Brain Research.  131: 477-490.

MacKinnon, C.D., Kapur, S., Hussey, D., Verrier, M.C., Houle, S., Tatton, W.G. (1996) Contributions of the mesial frontal cortex to the premovement potentials associated with intermittent hand movements in humans.  Human Brain Mapping.  4(1): 1-22.

MacKinnon, C.D., Winter, D.A.  (1993) Control of balance and posture in the frontal plane during human walking. Journal of Biomechanics.  26(6): 633-644.

 Last updated onJanuary 28, 2007

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