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Residency


- Assistant Professor of Anesthesiology
Training / Education

Undergraduate
University of California at Berkeley 

Graduate
Columbia University (MA in Genetics and Development)
Columbia University (PhD in Biology)

Fellowship
Harvard Medical School and Massachusetts General Hospital (Postdoctoral Fellow)

Research & Bibliography

Publications

 Sage, C., Huang, M., Karimi, K., Gutierrez, G., Vollrath, M. A.,  Zhang, D.-S., García-Añoveros, J., Hinds, P. W., Corwin, J. T., Corey, D. P, and Chen, Z.-Y. (2005). Proliferation of functional hair cells in vivo in the absence of retinoblastoma protein. Science 307, 1114-8. (Epub13 January, 2005).
Comentaries on and Evaluations of this paper:
-Taylor R, Forge A. (2005). Developmental biology. Life after deaf for hair cells? Science 307, 1056-8.
-F1000 factor 6.0 (Must Read)

*Corey, D. P., *García-Añoveros, J., *Holt, J. R., *Kwan, K Y., *Lin, S.-Y., *Vollrath, M. A., Amalfitano, A., Cheung, E. M.-L., Derfler, B. H., Duggan, A., Géléoc, G. S. G., Gray, P., Hoffman, M. P., Rehm, H. L., Tamasauskas, D., and Zhang, D.-S. (2004). TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature 432, 723 - 730 (AOL 13 October 2004). *Equal contribution.
Comentaries on and Evaluations of this paper:
-Ashmore, J. (2004). News and Views -Hearing: Channel at the hair's end. Nature 432, 685.
-Jones, R. (2004) Res. Highlights -A great TRP for hair cells. Nat Rev Neurosci 5, 898-9.
-Barritt G, Rychkov G. (2005). TRPs as mechanosensitive channels. Nat Cell Biol. 7, 105-7.
-F1000 factor 11.0 (Exceptional)  Highest ranked paper for all biology (
9 November 2004)

Duggan, A., García-Añoveros, J. and Corey, D. P. (2002). The PDZ domain protein PICK1 and the sodium channel BNaC1 interact and localize at mechanosensory terminals of dorsal root ganglion neurons and dendrites of central neurons. J. Biol. Chem. 277, 5203-5208.

 García-Añoveros, J., Samad, T., Žuvela-Jelaska, L., Woolf, C. J., and Corey, D. P. (2001) Transport and localization of the DEG/ENaC ion channel BNaC1á to peripheral mechanosensory terminals of DRG neurons. J. Neurosci.  21 (8), 2678-2686.

Duggan, A., García-Añoveros, J., and Corey, D. P. (2000). Insect mechanoreception: What a long, strange TRP it's been. Current Biology 10, R384-387.

García-Añoveros, J., García, J. A., Liu, J., and Corey, D. P.  (1998) The nematode degenerin UNC-105 forms ion channels that are activated by degeneration- or hypercontraction causing mutations. Neuron 20, 1231-1241.

García-Añoveros, J., and Corey, D. P. (1997).  The molecules of mechanosensation. Annu. Rev. Neurosci. 20, 567-594.

García-Añoveros, J., Derfler, B., Neville-Golden, J., Hyman, B. T., and Corey, D. P. (1997).  BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels. Proc. Natl. Acad. Sci. USA  94, 1459-1464.

Hall, D. H., Gu, G., García-Añoveros, J., Gong, L., Chalfie, M., and Driscoll, M. (1997).  Neuropathology of degenerative cell death in Caenorhabditis elegans. J. Neurosci.  17, 1033-1045.

Corey, D. P., and García-Añoveros, J. (1996).  Mechanosensation and the DEG/ENaC ion channels. Science 273, 323-324.

García-Añoveros, J., and Corey, D. P. (1996).  Mechanosensation: Touch at the molecular level. Current Biology 6, 541-543.

García-Añoveros, J., Ma, C., and Chalfie, M. (1995). Regulation of Caenorhabditis elegans  degenerin proteins by a putative extracellular domain. Current Biology 5, 441-448.

Otsuka, A. J., Jeyaprakash, A., García-Añoveros, J., Tang, L. Z., Fisk, G., Hartshorne, T., Franco, R., and Born, T. (1991). The C. elegans unc-104 gene encodes a putative kinesin heavy chain-like protein. Neuron 6, 113-122.

Gotesdiener, K., García-Añoveros, J., Lee, M. G. S., and Van der Ploeg, L. H. T. (1990). Chromosome organization of the protozoan Trypanosoma brucei. Molecular Cell Biology.  10 (11), 6079-6083.

Invited Presentations

2005    Dept of Cell Biology, Neurobiology & Anatomy, Loyola University Medical Center. Chicago, IL 

2004    Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD.

2003    Department of Neuroscience, University of Virginia, Charlottesville, VA. 

2003    American Pain Society Meeting Symposium: Ion Channels Underlying the Response to Physical Stimuli. Chicago, IL.

2002    Department of Biology, Illinois State University, Normal, IL.

2001    Session leader at Gordon Conference: Mechanosensation. New London, CT. 

2000    3rd International Symposium: The ENaC/Degenerins Gene Superfamily: From Molecules to diseases. Villars-sur-Ollon, Switzerland.

2000    Fundación March Workshop: The molecules of pain: molecular approaches to pain research. Madrid, Spain.

1998    Gordon Conference: Gravitational Effects on Living Systems. New London, NH.

 

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Department of Anesthesiology
Northwestern University, Feinberg School of Medicine
251 E. Huron St, F5-704
Chicago, IL 60611
Telephone: 312/926-8105
Fax: 312/926-9206

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