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Cleaver Group

Ondine Cleaver, PhD

UT Southwestern Medical Center
Dallas, Texas, USA

 We study vascular cell fate and how progenitor cells assemble into blood vessels. Our group is particularly interested in intracellular signaling events that drive cytoskeletal or adhesion changes within progenitor cells, allowing them to assemble into functional tissues. We are interested in how cues in the microenvironment drive vascular assembly or growth, and how blood vessels in turn communicate paracrine, non-nutritional signals to stem cell niches. We also study how blood vessels maintain their integrity and how this can go awry due to genetic or hemodynamic defects.

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