Northwestern University Feinberg School of Medicine

Osher Center for Integrative Medicine at Northwestern University

Research Studies

The Osher Center for Integrative Medicine at Northwestern University is focused on clinical research that defines the value of Complementary and Integrative Medicine (CIM) practices in disease care and wellness. Below is a selected list of our current active protocols.

Eva Shiu, MPHJudith T. Moskowitz, PhD

Lessons in Affect Regulation to Keep Stress and Pain UndeR control (LARKSPUR)

A positive emotion intervention for people living with chronic musculoskeletal pain. Chronic pain is the leading reason people seek complementary or integrative health (CIH) care and although a number of treatments have been shown to be effective for pain, suboptimal adherence to the treatment plan lowers the efficacy of otherwise promising treatments. This project aims to develop and test a positive emotion intervention tailored for people living with chronic musculoskeletal pain to optimize effects on depression, adherence, and pain intensity and interference in conjunction with integrative or conventional treatments for pain.

Eva Shiu, MPHJudith Moskowitz, PhD

LEAF: Life Enhancing Activities for Family Caregivers

A positive emotion intervention for caregivers of patients with Alzheimer’s Dementia. Caregiving burden has a deleterious impact on caregiving quality and quality of life in the care recipient. Interventions for dementia caregivers have primarily focused on reducing negative emotions and burden. However, over the past few decades, it has become clear that positive emotions are uniquely related to better psychological and physical well-being, independent of the effects of negative emotion suggesting that an intervention that specifically targets positive emotion holds promise for improving caregiver well-being and, ultimately, quality of care for the individual living with AD. This project aims to develop and test a positive emotion intervention tailored for caregivers of patients with AD.

Inger Burnett-Zeigler, PhD

M-Body Study 

This project that examines the efficacy of a Mindfulness Based Stress Reduction (MBSR) intervention for depressed Women in a Federally Qualified Health Center. This study examines the acceptability and preliminary efficacy of a mindfulness based treatment for depression delivered to women in a community primary care setting. Responsibilities for this project include: assisting with recruitment, screening, baseline survey administration, administrative tasks such as attendance, handing out stipends, setting up food, and travel to the Oakland neighborhood on the south side

Veronika GroteElizabeth Addington, PhD

LYNC: Learning Yoga to eNhance Cancer survivorship

Internet-based yoga classes for young adult cancer survivors. Research findings suggest that cancer-adapted yoga delivered online in a live, group format has the potential to reach post-treatment young adult cancer survivors (YACS) and to ameliorate some of their most prevalent cancer-related psychosocial and physical symptoms. Accordingly, this project will develop and pilot cancer-adapted yoga classes delivered via internet-based multipoint videoconferencing to post-treatment YACS. In the first phase of the project, we will conduct focus groups with yoga instructors and YACS to tailor the yoga intervention.

Veronika GroteElfriede Pahl, MD

ROSE: Resilience Intervention for pre-Operative Stress and Emotion

Despite the excellent survival rate, many transplanted children suffer from poor quality of life (QOL), limited exercise endurance, and continued limitations to their well-being. Research shows that QOL in patients with congenital heart disease (CHD), and more so children with heart failure, is significantly lower than in normal children. The purpose of the current project is to improve overall QOL by introducing positive emotion skills to reduce anxiety and stress during pre-transplant waiting time for pediatric heart recipients and their parents. We hope this will have a direct effect on post -transplant recovery, satisfaction, and caregiver stress.

Bonnie Essner, PhD

Shadow’s Edge®

The purpose of this study is to evaluate the effectiveness of Shadow’s Edge®, a mobile game developed to promote empowerment, enhance emotional resilience and encourage identity formation among adolescents and young adults with chronic health conditions.

Co-investigators: Edna Romero, PhD, Jennifer Reichek, MD, Joel E Frader, MD

Veronika GroteJudith Moskowitz, PhD

PEACE NU: Positive psychology for acute coronary syndrome patients: a randomized, controlled pilot trial

Health behaviors play a major role in the prevention of new and reoccurring health conditions like acute coronary syndromes (ACS). The current study aims to examine the feasibility, acceptability, and impact of a 12-week, telephone-based positive psychology intervention on mental and physical health, functioning, and health behaviors in a randomized, controlled pilot trial.