Division of Reproductive Science and Medicine
Dr. Chakravarti received his PhD from Albert Einstein College of Medicine, New York, in 1992. Until 1998, he was a Jane Coffin Childs Memorial Fund Postdoctoral Fellow in the laboratory of Dr. Ron Evans at the Salk Institute, La Jolla, California. Dr. Chakravarti was an assistant professor at the University of Pennsylvania prior to his arrival at Northwestern University in 2005. One of the major research interests of Dr. Chakravarti is to determine the mechanisms of steroid hormone and vitamin signaling with special emphasis on the role of the nuclear hormone receptor co-regulatory proteins in gene transcription. Modulation of chromatin modification is essential for gene expression and therefore its alteration has been linked to human diseases including cancer. Dr. Chakravarti's laboratory identifies and characterizes the role of chromatin signal transducer proteins including the recently identified INHAT proteins in gene regulation. Dr. Chakravarti's laboratory is also characterizing members of a novel THAP domain protein family regarding their roles in gene regulation, chromatin signaling, cell growth and differentiation, and cancer.
Individuals interested in the Chakravarti Lab should contact lab director, Debu Chakravarti.