Our research in bacteriology focuses primarily on the analysis of microbe-host interactions. The department faculty study mechanisms underlying bacterial colonization and pathogenesis in diverse species: pathogenic Legionella, Neisseria, Pseudomonas, Vibrio, and Yersinia species, and in beneficial Vibrio fischeri. Work from the bacteriology laboratories has provided novel insights into bacterial-host specificity and interaction, mechanisms of metal acquisition by bacterial pathogens, the transcriptional and post-transcriptional regulation of factors required for virulence, molecular changes that underlie key evolutionary transitions, and the influence of DNA structure on gene expression.
Labs in This Research Area
Pathogenesis of Legionella pneumophila and Stenotrophomonas maltophilia
Pathogenesis of Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae infections
Role of bacterial protein toxins in the pathogenesis of Vibrio vulnificus and Vibrio cholerae
Bacterial pathogenesis, DNA recombination mechanisms, epithelial cell adherence
Molecular mechanisms of ribosome hibernation and antibiotic resistance