Northwestern University Feinberg School of Medicine
Driskill Graduate Program in Life Sciences
Paul T Schumacker, PhD

Paul T Schumacker, PhD

Professor of Pediatrics (Neonatology), Cell and Developmental Biology and Medicine (Pulmonary and Critical Care)

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Focus of Work

Bio

Our lab is interested in the effects of oxygen on cell metabolism, and in the molecular mechanisms underlying cellular oxygen sensing. The signaling pathways activated by hypoxia, and their regulation of transcriptional and post-translational responses in diverse cell types are also of major interest. Current studies focus on the role of mitochondrial redox signaling in the development of pulmonary hypertension. Other current studies focus on cardiomyocyte regeneration in the heart and molecul...[Read full text]Our lab is interested in the effects of oxygen on cell metabolism, and in the molecular mechanisms underlying cellular oxygen sensing. The signaling pathways activated by hypoxia, and their regulation of transcriptional and post-translational responses in diverse cell types are also of major interest. Current studies focus on the role of mitochondrial redox signaling in the development of pulmonary hypertension. Other current studies focus on cardiomyocyte regeneration in the heart and molecular factors that regulate hypertrophic and hyperplastic remodeling responses.[Shorten text]

Keywords

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Cardiovascular DiseasesPulmonary HypertensionCancer BiologyMetabolismParkinson’s DiseaseLungs / Breathing ProblemsCell BiologySignal Transduction

Education and Certification

  • PhD: Albany Medical College, Physiology (1980)

Contact

Administrative office: 312-503-1475
Laboratory: 312-503-1476

Morton Building Room 4-685
310 E Superior
Chicago IL 60611

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