Rintaro Hashizume, MD, PhD
Assistant Professor, Biochemistry and Molecular Genetics; Feinberg School of Medicine
Understanding molecular mechanisms, that affect the aggressive/infiltrative biological behavior of malignant brain tumor and would accordingly reveal potential therapeutic targets for cancer therapy. My laboratory employs the latest genomic/epigenomic technologies to identify new therapeutic targets, and test the anti-tumor activity of the therapeutics using patient-derived pediatric brain tumor mouse model system. Our current efforts have been to identify epigenetic targets in pediatric brain tumors. I expanded my research to include understanding molecular mechanisms and developing animal model of pediatric brain tumor for preclinical testing of molecular targeting therapeutics.