Northwestern University Feinberg School of Medicine

Asher Center for the Study and Treatment of Depressive Disorders

Affective Science and Treatment Laboratory

The Affective Science and Treatment lab is focused on identifying novel bio-behavioral mechanisms of treatment response for depression and perinatal depression, tracking change and deficits in emotion and motivation in women across the lifespan, and testing predictors and mechanisms of successful response to Behavioral Activation treatment for depression.

Current Research

  1. Track substrates of emotion in women from pregnancy to postpartum.

  2. Detect the neural bases of emotion and neurocognition in women across the lifespan.

  3. Identify bio-behavioral substrates of emotion and affective learning in depression and anxiety.

  4. Testing mechanisms and predictors of Behavioral Activation.

  5. Installing Behavioral Activation Communication, a novel milieu approach, into acute inpatient psychiatric units (now used at Northwestern Memorial Hospital and other US medical centers).

Our Facilities

Housed in the Asher Center for the Study and Treatment of Depression, 676 North St. Clair Street, Suite 1000, Chicago, Illinois, our lab has space for structured interviewing, neurocognitive testing, implicit stimulus presentations, and data analyses for neuroimaging data (SPM) and psychophysiological protocols.

Our Success

Recent Publications

Recent lab publications are available via the faculty profile of director Jackie Gollan, PhD.


A.T. Beck and Brown University Award, Brown University Medical School (1999), Summer Fellow, National Institutes of Health, Office of Behavioral and Social Sciences Research (2002), Fellow, Stanford University & University of Pittsburgh Collaborative Research Institute (2003), Pioneer Award, Institute for Women’s Health Research, Northwestern University (2008), Steiner Young Investigator Award (2012).

Grants and Funding

National Institute of Mental Health, R21 1R21MH082133 (PI), 1R01MH084904-01A2 (Co-Inv), R01 MH072850 (Co-Inv), National Alliance for Research on Schizophrenia and Depression and Education Foundation of America (PI), Ken and Ruth Davee Award for Innovative Investigations in Affective Disorders, Brain Research Foundation, Braun Family Northwestern University, Greek Orthodox Ladies Philoptochos Society, Institute of Women's Health Research Pioneer Program, Evergreen Invitational Women’s Health Grant Initiative, Women’s Board of Northwestern Memorial Hospital.

Contact Us

Contact Jackie Gollan, PhD, Director, for more information about the Affective Science and Treatment Laboratory.

Jackie Gollan, PhD

Graduate Students

Jennifer Gowans
Maureen Satyshur