Northwestern University Feinberg School of Medicine

Asher Center for the Study and Treatment of Depressive Disorders

Biomarkers of Inflammation In Perinatal Depression In Women Undergoing A Scheduled Cesarean

Northwestern University IRB: STU00084230
Principal Investigator:Katherine L. Wisner, MD MS and Emily Miller, MD MPH (Department of Obstetrics and Gynecology)

Depression around the time of childbirth is one of the most common and, potentially, one of the most devastating complications of pregnancy. This research represents an innovative approach toward examining the neurobiochemical pathways of depression. Your participation will open the door toward improving the diagnosis of perinatal depression and developing targeted therapies.

Women undergoing a scheduled cesarean section may be eligible. Participants will be screened for inclusion when they come to the hospital for their cesarean. Those who are eligible for participation will fill out surveys and do a clinical interview with a member of our team before leaving the hospital (on average this takes less than 60 minutes total to complete). In addition, a blood sample is taken at the same time that the nurse starts the IV and cerebrospinal fluid (CSF) is taken at the same time as the anesthesia team is placing the spinal for the surgery. There are no extra procedures being done beyond what is required for routine care. Finally a survey is completed at the same time as the postpartum appointment. Participants will receive $50 for completing the study.

Participants will be eligible for the study if they:

Participants will not be eligible for the study if they:

If you are interested in participating or would like to hear more information, please email research coordinator or call 1-855-99-ASHER.