Northwestern University Feinberg School of Medicine

Asher Center for the Study and Treatment of Depressive Disorders

Optimizing Medication Management for Mothers with Depression (OPTI-MOM)

Northwestern University IRB:STU00201386
Principal Investigators: Katherine L. Wisner, MD MS (Psychiatry), Catherine Stika, MD (Obstetrics), Alfred George, MD (Pharmacology)

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is sponsoring a study here at Northwestern Medicine to optimize medication management for women who take antidepressants during pregnancy.

Why is this research important?
Depression in pregnancy affects one in seven mothers and causes suffering to mothers and risks to the healthy development of their children.  How to treat women optimally during pregnancy will be determined by this research. 

Many women take antidepressants during pregnancy to help manage their mood symptoms, but additional information is needed to help providers optimize treatment.

Your participation in this study may lead to knowledge that can help improve SSRI treatment for other mothers in the future.   Our expert team will also communicate with your current prescriber to provide additional monitoring during this important time.

You may be eligible to participate if you:

Study Includes:

Compensation Includes:

If you are interested in participating or would like to hear more information, please contact our research team at or 1-855-99-ASHER.