Northwestern University Feinberg School of Medicine

Asher Center for the Study and Treatment of Depressive Disorders

Fetal and Newborn Signs After Maternal Antidepressant Treatment (FANSMAT)

Northwestern University IRB: STU00205927

Principal Investigators: Laura Rasmussen-Torvik, PhD MPH (Epidemiology)

The Friends of Prentice at Northwestern Memorial Hospital is funding a study here at Northwestern University to investigate Neonatal Adaptation Syndrome in infants exposed to antidepressants.

Why is this research important?

The overall goal of the FANSMAT study is the optimization of antidepressant treatment during pregnancy. A critical aspect of optimization is to manage maternal symptoms while minimizing exposure of the fetus to the medication.  Neonatal Adaptation Syndrome (NAS) is the name given to a group of symptoms that sometimes occur in newborns exposed to medication during pregnancy.

In this study we will examine maternal blood and cord blood antidepressant concentrations as well as maternal and infant genetic factors to evaluate their relationship to the development of NAS. Examining both predictors for NAS and the evolution of signs across the neonatal period will provide overdue insight into the underlying mechanism(s) and support development of an optimal approach to SSRI treatment for pregnant women.  The ultimate goal of this research is to develop tailored treatment for the prevention of NAS.

You may be eligible to participate if you:

 Study Includes:

Compensation Includes:

If you are interested in participating or would like to hear more information, please contact our research team at or 1-855-99-ASHER.