Epidemiology

• Definition
• Prevalence and Epidemiology
• Fracture Incidence vs. Heart attack, Stroke, etc.
• Risk Factors
• Fracture Risk with Aging
• History of Fracture and Hip Fracture Risk

Diagnoses

• World Health Organization Information
• Parathyroid Physiology
• Metabolism of Vitamin D
• Hip Fracture
• BMD Testing
• Who should have a BMD Test
• Diseases Associated with Bone Loss
• Medical Conditions that increase Risk
• Medications Associated with Reduced Bone Mass

Treatment

• Prevention and Treatment
• NOF Recommendations
• FDA approved options
• Alendronate
• Risedronate
• Estrogen- FDA
• Parathyroid Hormone
• Teriparatide Fracture Results
• Teriparatide Adverse effects
• SERMS
  

Primary Prevention

• Rx for strong bones
• Exercise

Secondary Prevention - Fractures

• History of fracture predicts hip fracture risk

• Accelerated bone loss

• Effect on gait

• Targeting high-risk patients for intervention.

• A history of fracture predicts hip fracture risk

• Accelerated bone loss

• Effect on gait

• Targeting high-risk patients for intervention

Current Clinical Guidelines

• Northwestern Medical Faculty Foundation

• Northwestern Memorial Hospital

• National Osteoporosis Foundation 1998

• American Association of Clinical Endocrinologists, 2001

• American Council on Rheumatology, 2001

Valuable Links for Bone and Mineral Research

• American Society of Bone and Mineral Research

• IBMS Bone Key-osteovision

• NIH Osteoporosis and Related Bone Disease National Resource Center

• National Osteoporosis Foundation

• International Osteoporosis Foundation

• The Paget’s Foundation

• Osteogenesis Imperfecta

• X-linked Hypophosphatemic Rickets

• National Institutes of Health

• National Institutes on Aging

• National Institute of Arthritis and Musculoskeletal Diseases

• National Institute on Alcohol Abuse and Alcoholism

• NIH Consensus Conference on Osteoporosis

• American Academy of Clinical Endocrinologists (Post Menopausal Osteoporosis)

• American Academy of Clinical Endocrinologists (Hypogonadism)

• American Academy of Clinical Endocrinologists (WHI)

• American Academy of Clinical Endocrinologists (Menopause)
  

Glucocorticoid Induced Osteoporosis

• Diagram of pathopysiology

• Pathophysiology

• Glucocorticoid Induced Osteoporosis

• Glucocorticoid Use

Osteoporosis in Women

• Menopause and Bone Loss

• Bone Loss and HRT

• Estrogen Discontinuation

• Epidemiology

Osteoporosis in Men

• Epidemiology

• Risk Factors: Men

• Risk Gender and Hypogonadism

• Diagnosis

• Treatment

Diseases Associated with Bones Loss 

• Pulmonary: COPD, cystic fibrosis, emphysema

• Rheumatologic: Systematic lupus, rheumatoid arthritis

• Gastronintestional: Malabsorption, celiac disease, inflammatory bowel disorder, Crohn's disease, u/c colitis, short bowel syndrome, hronic TPN, chronic liver disease, primary biliary cirrhosis, liver transplant, alcoholic cirrhosis

• Neurologic: Anticonvulsant use (adolescents)

• Cardivascular: Chronic anticoagulation, coumadic, hepititus

• Nutrition: Anorexia nervosa, bulimia

• Ob/Gyn: Prolonged amernorrhea

Allied Associated Health Services

Vertebroplasty-Kyphoplasty

Orthopaedic Surgery:

Mathew Hepler

(312) 695-6800

Neurosurgery:

John Liu

(312) 695-8143

Interventional Radiology:

Eric Russell

(312) 695-5753

Other Densitometers:

Radiology:

(312) 926-2514

Ob & Gyn:

(312) 695-1000