My Northwestern Medicine October 29, 2025

Uncovering New Therapeutic Targets for Cancer Mutations

Uncovering New Therapeutic Targets for Cancer Mutations

A team of Northwestern investigators has discovered novel molecular underpinnings of a common oncogenic mutation in cancer, findings that may inform the development of new therapeutic strategies, according to findings published in Nature Chemical Biology.

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Obesity Drugs Regulate Neural Systems to Curb Appetite

A recent Northwestern Medicine study has identified novel neural circuits modulated by the diabetes and obesity-management drugs semaglutide and tirzepatide that help suppress appetite.

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New Study Gives Answers, Drug Targets for Chronic Lung-transplant Rejection

A new Northwestern Medicine study has found that, following transplant and in chronic disease states, abnormal cells emerge and “conversations” between them drive the development of transplant rejection.

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Head Inside the OR to Witness an Open Heart Surgery

S. Christopher Makaisrie, MD explains the treatment process on an aortic aneurysm while performing surgery in the Bluhm Cardiovascular Institute.

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Career Pipeline Program Opens Doors in Supply Chain for Chicago Residents

Working with a local workforce development organization, the program gives residents on Chicago’s West and South sides the skills they need to start a successful career at Northwestern Medicine.

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