Most Recent Publications

• Mutant p53 promotes clonal hematopoiesis by generating a chronic inflammatory microenvironment.

  Chen S, Barajas S, Vemula S, Yang Y, Simpson E, Gao H, Li R, Behzadnia F, Nabinger SC, Schmitz DA, Chen H, Cai W, Xiao S, Luo R, Amin MA, Capitano ML, Ropa JP, Fahey A, Zhou S, Mays TM, Sotelo M, Pan H, Hu SK, Veranga S, Ali M, Shumilina M, Kapur R, Ren K, Jia Y, Liu H, Khan I, Abaza Y, Altman JK, Eklund EA, Godley LA, Zhang CR, Ji P, Masters SL, Croker BA, Boswell HS, Sandusky GE, Gao Z, Mayo LD, Savage SA, Halene S, Dou Y, Platanias LC, Sukhanova M, Liu Y, Abdel-Wahab O, Liu Y

  J Clin Invest. 2026 Feb; 136(3):

  https://doi.org/10.1172/JCI184285

  PMID: 41468163
• FBXO11 suppression rewires an NPM1-centered interactome influencing the progression of myelodysplastic syndrome.

  Niederkorn M, Bezavada L, Cotton A, Palmer LE, Konada L, Hall T, Pagala VR, Zhai J, Yuan Z-F, Fu Y, Steele JA, Narina S, Schild A, Wu C, Aminov S, Schieber M, McGovern E, Taylor AB, Gurbuxani S, Xu P, Ji P, Janke LJ, High AA, Kang G, Pruett-Miller SM, Weiss M, Verma A, Rampal RK, Crispino JD

  J Clin Invest. 2026 Jan; 136(2):

  https://doi.org/10.1172/JCI193636

  PMID: 41542766
• Overall cancer risk in people with deleterious germline DDX41 variants.

  Korotev SC, Cheng JX, Haribabu Y, Strauss J, Dominguez S, Koppayi A, Perpich M, Pies M, Moma L, Kim A, Basdag H, Rodgers C, Kosuri S, Saiki R, Makishima H, Tawde S, Galasinski S, Kandikatla P, Subramanian HP, Ren K, Bi H, Mohammadhosseini M, Ogawa S, Ji P, Agarwal A, Das S, Godley LA

  Haematologica. 2025 Sep; 110(9): 2076-2090.

  https://doi.org/10.3324/haematol.2024.286887

  PMID: 39945023
• DDX41 resolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death.

  Bi H, Ren K, Wang P, Li E, Han X, Wang W, Yang J, Aydemir I, Tao K, Ma R, Godley LA, Liu Y, Shukla V, Bartom ET, Tang Y, Blanc L, Sukhanova M, Ji P

  Nat Commun. 2025 Aug; 16(1): 7195-.

  https://doi.org/10.1038/s41467-025-62307-7

  PMID: 40764304