Northwestern University Feinberg School of Medicine

Department of Obstetrics and Gynecology

Current Clinical Trials in the Department of Obstetrics & Gynecology

Study Name

Description

Division(s)
Principal Investigator
Contact(s)
Progesterone receptor modulation for endometriosis-related pelvic painThe aim of this study is to assess ulipristal acetate for treatment of chronic pelvic pain in patients with refractory endometriosisReproductive Endocrinology & Infertility (REI)Serdar Bulun, MD

Sarah Cuneo

sarah.cuneo@nm.org

Buccal misoprostol prior to abdominal myomectomy for reduction of intraoperative blood loss: a randomized placebo-controlled trial

The aim of this study is to evaluate the use of a preoperative medication, buccal misoprostol, for reducing blood loss during fibroid removal surgery (myomectomy)

Minimally Invasive Gynecologic Surgery (MIGS), Reproductive Endocrinology & InfertilityMagdy Milad, MD

Dana Posley

dana.posley@northwestern.edu

Optimal treatment for women with Persisting Pregnancy of Unknown Location - a Randomized Clinical Trial of women at risk for an ectopic pregnancy: Active Treatment versus Expectant Management (No Treatment) “The ACTorNOT Trial”

The aim of this study is to evaluate three different management strategies in pregnant women who have persisting pregnancies of unknown location (PPUL) to determine the most effective at resolving a PPUL without requiring any additional treatment afterwards.

Reproductive Endocrinology & Infertility (REI)

Jared Robins, MD

reiresearch@nm.org or (312) 503-4118

Development of a non-invasive prenatal screening test for multiple gestation pregnancies based on fetal DNA isolated from maternal blood

The aim of this study is to develop a method of minimally invasive prenatal diagnosis for multiple gestation pregnancies that has a higher sensitivity and lower false positive rate than current available screening tests.

Reproductive Endocrinology & Infertility (REI)

Jared Robins, MD

reiresearch@nm.org or (312) 503-4118

Serum and Plasma Bank for the Development of Novel Ectopic Pregnancy Biomarkers

The aim of this study is to collect and retain blood samples from women who present with pain and/or bleeding in early pregnancy (up to 14 weeks) to identify novel biomarkers that distinguish normal pregnancy from ectopic pregnancy.

Reproductive Endocrinology & Infertility (REI)

Jared Robins, MD

reiresearch@nm.org or (312) 503-4118

Folic Acid and Zinc Supplementation Trial

The aim of this study is to assess the impact of folic acid and zinc dietary supplementation in males on semen quality and fertility outcomes (i.e., live birth rate) among couples attempting to conceive and seeking assisted reproduction.

Reproductive Endocrinology & Infertility (REI)

Jared Robins, MD

fazst@northwestern.edu or (312) 503-4118

A Randomized Double Blind Clinical Trial Comparing Oxytocin Low-Dose and High-Dose Regimens for Labor Augmentation

A double blind randomized clinical trial comparing low-dose and high-dose oxytocin regimens in consenting women giving birth for the first time, in spontaneous labor but without delayed labor progress

Maternal-Fetal Medicine (MFM)

Alan Peaceman, MD

amp066@northwestern.edu