Northwestern University Feinberg School of Medicine

Department of Obstetrics and Gynecology

Matei Lab

Laboratory Focus

Daniela Matei, MD, a leading ovarian cancer researcher and oncologist, has joined the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Dr. Matei is a Professor of Gynecologic Oncology and Hematology/Oncology at Northwestern University Feinberg School of Medicine, and will play a key role within the Lurie Cancer Center as Co-Leader of the Women’s Cancer Research Program (WC).

Dr. Matei joins Northwestern from the Indiana University School of Medicine, where she was a Professor in the Departments of Medicine and Obstetrics and Gynecology, and Co-Leader of Melvin and Bren Simon Cancer Center’s Experimental and Developmental Therapeutics Program –coordinating drug development efforts at the bench and in the clinic. Her laboratory studies mechanisms of ovarian cancer metastasis and novel therapeutics for ovarian cancer.

One direction of Matei’s current research focuses on finding new treatments to eradicate ovarian cancer stem cells and improve outcomes for women with this deadly cancer. Another area of investigation is to target the epigenome and re-establish response to chemotherapy for ovarian tumors that have become resistant to treatment. Matei is actively engaged in clinical research and is involved in numerous clinical trials that test novel therapies for ovarian cancer, including several cooperative group and National Cancer Institute-sponsored trials for gynecologic cancers. She was the recipient of several awards for significant contributions to clinical or basic science cancer research.

In collaboration with David Gius, MD, PhD, and Seema Khan, MD, Matei’s focus on translating discoveries into clinical applications will enhance the vision of the Women’s Cancer Research Program. The program embraces a multidisciplinary approach to integrate its basic science, clinical and translational elements. The goal of the WC is to advance understanding of breast and gynecologic cancers – identifying the molecular markers that contribute to disease process and outcome, and developing targeted, personalized approaches.

Learn more about the Matei Laboratory:

Daniela E Matei, MD

Daniela E Matei, MD

Diana, Princess of Wales Professor of Cancer Research

Professor in Medicine-Hematology/Oncology and Obstetrics and Gynecology-Gynecologic Oncology