Northwestern University Feinberg School of Medicine

Center for Diabetes and Metabolism

Stephen D Miller, PhD

Stephen D Miller, PhD

Director, Interdepartmental Immunobiology Center

Judy Gugenheim Research Professor of Microbiology-Immunology

Professor of Microbiology-Immunology and Dermatology

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Focus of Work

Bio

The laboratory is interested in understanding the mechanisms underlying the pathogenesis and immunoregulation of T cell-mediated autoimmune diseases, allergic disease, and rejection of tissue and organ transplants. In particular, we are studying the therapeutic use of short-term administration of costimulatory molecule agonists/antagonists and specific immune tolerance induced by infusion of antigen-coupled apoptotic cells and PLG nanoparticles for the treatment of animal models of multiple scl...[Read full text]The laboratory is interested in understanding the mechanisms underlying the pathogenesis and immunoregulation of T cell-mediated autoimmune diseases, allergic disease, and rejection of tissue and organ transplants. In particular, we are studying the therapeutic use of short-term administration of costimulatory molecule agonists/antagonists and specific immune tolerance induced by infusion of antigen-coupled apoptotic cells and PLG nanoparticles for the treatment of animal models of multiple sclerosis and type 1 diabetes, allergic airway disease, as well as using tolerance for specific prevention of rejection of allogeneic and xenogeneic tissue and organ transplants.[Shorten text]

Keywords

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Autoimmune DiseasesImmune RegulationImmunologyMultiple SclerosisViral PathogenesisDiabetes, Endocrine and MetabolismNeuroscienceTransplantation

Education and Certification

  • PhD: Pennsylvania State University, MicroImmunology (1975)
  • Postdoctoral Fellowship: University of Colorado, Cellular Immunology (1978)

Contact

312-503-7674
312-503-0489

Tarry Building Room 6-713
300 E Superior
Chicago IL 60611

Links

Institutes and Centers