Northwestern University Feinberg School of Medicine

Driskill Graduate Program in Life Sciences

Jacek  Topczewski, PhD

Jacek Topczewski, PhD

Research Associate Professor of Pediatrics (Developmental Behavioral Pediatrics)

Focus of Work

Bio

1983-1988 M.Sc. University of Warsaw, Poland - Biology / Biochemistry 1989-1996 Ph.D. Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland - Biology / Biochemistry 1997-2002 Research Associate with Dr. Lilianna Solnica-Krezel, Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee - Zebrafish developmental Biology

Academic Focus

My research focuses on the application of the zebrafish model to study biological processes underlying human disorders. I am particularly interested in the processes that control formation of cartilages and bone. My laboratory study the role of heparin sulfate proteoglycans from the glypican family in this process and their relation to Wnt/PCP pathway regulating cell polarity and movements. In addition, we investigate the role of cholesterol biosynthesis in the process of skeletogenesis.
In se...[Read full text]
My research focuses on the application of the zebrafish model to study biological processes underlying human disorders. I am particularly interested in the processes that control formation of cartilages and bone. My laboratory study the role of heparin sulfate proteoglycans from the glypican family in this process and their relation to Wnt/PCP pathway regulating cell polarity and movements. In addition, we investigate the role of cholesterol biosynthesis in the process of skeletogenesis.
In several collaborative projects, I am involved in developing zebrafish model of pediatric disease and cancers.[Shorten text]

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Education and Certification

  • PhD: Polish Academy of Science, Warsaw (1996)

Contact

Administrative office: 773-755-6545

Stanley Manne Children’s Research Institute Box 204
225 East Chicago Avenue
Chicago IL 60611