The Center for Translational Metabolism and Health at Northwestern University is one of four recipients of the new American Heart Association Strategically Focused Research Network (SFRN) Center that is focused on Health Disparities. The Co-Directors of the Northwestern University Center are Dr. Mercedes Carnethon and Dr. Myles Wolf, and the Director of the associated Fellowship training program is Dr. Clyde Yancy. The overall objective of the Northwestern University SFRN Center is to identify novel modifiable mechanisms of the disparate prevalence of cardiovascular disease and chronic kidney disease among racial and socioeconomic minorities. The three primary research projects that the Northwestern Center will conduct include:
- Basic: Molecular Mechanisms of Cardiac Injury Induced by FGF23 in the Settings of High Phosphate Diet and CKD; Principal Investigator: Myles Wolf, MD, MMSc
- Clinical: Impact of Lowering Phosphate Additive Intake on Mineral Metabolism and Cardiovascular Health in Community-living Adults; Principal Investigator: Orlando Gutierrez, MD, MMSc
- Population: Contribution of Fibroblast Growth Factor 23 to Racial Disparities in Left Ventricular Mass and Albumin to Creatinine Ratio; Principal Investigator: Dr. Mercedes Carnethon, PhD, FAHA
The Northwestern SFRN Center supports two-year postdoctoral fellowship positions for individuals interested in advanced training in disparities research. Postdoctoral Disparities Research Fellows in our program are trained in both the science that underpins disparities in cardiovascular and kidney health and the application of research tools to investigate and ultimately eliminate these disparities. Our highly individualized 2-year training program offers basic, clinical, population, and social science experiences while providing opportunities to develop close mentoring relationships with senior investigators in a unique multi-institutional research network. This structure distinguishes the Disparities SFRN Training Program from other educational experiences at Northwestern and nationally, and aims to move us closer to health equity.