Northwestern University IRB: STU00202090
Principal Investigators: Katherine L. Wisner, MD MS (Department of Psychiatry), Catherine Stika, MD (Department of Obstetrics and Gynecology), Alfred George, MD (Department of Pharmacology)
Why is this research study important?
Preeclampsia is a serious medical condition affecting pregnancy. Certain chemicals in your blood may increase your risk of developing preeclampsia. A medicine called pravastatin, which you take by mouth, may decrease the levels of these chemicals. The purpose of this pilot study is to determine how the body handles Pravastatin during pregnancy and to determine its safety.
You may be eligible to participate if you:
- Are 18 years or older
- Currently between 12-16 weeks pregnant
- Have a documented history of prior severe PE, requiring delivery before 35 weeks gestation
You are not able to participate if you:
- Have a history or myopathy or rhabdomyolysis
- Have active liver disease in the past 6 months
- Are using statins in your current pregnancy
- Take medications that interfere with statins
- Blood draws
- Randomization to pravastatin or placebo
- 3 extended study day visits
- Follow up visits throughout the course of your pregnancy
Participants will be compensated:
- Compensation per study visit in the amount of $25 for each visit in which your blood is drawn and $300 for each of the extended study day visits.
- Validation for on-site parking
For more information, please contact Kelly O'Shea at 1-855-99-ASHER, or email firstname.lastname@example.org