Northwestern University IRB: STU00079810
Principal Investigator:Crystal T. Clark, MD, MSc
Lamictal (lamotrigine) is an FDA approved drug commonly used to treat Bipolar Disorder. Because Bipolar Disorder frequently affects women during their reproductive years, the goal of this research study, led by Dr. Crystal Clark, is to understand how the dose of Lamictal should be modified for women who are pregnant. By participating in this study, you can help optimize the quality of care for women with Bipolar Disorder. At your initial visit, you will complete a full psychiatric evaluation with Dr. Clark at no cost to you. At each subsequent visit, you will stay overnight in the clinical research unit and complete assessments to monitor your mood, as well as blood draws to monitor your lamotrigine levels. As compensation, you will receive reimbursement for on-site parking or public transportation, financial compensation between $85-110 for every study visit you complete, for a total of up to $570; medical consultation with Dr. Crystal Clark about the best treatment for you throughout pregnancy; gifts for you and your baby and careful monitoring of your mood symptoms throughout pregnancy at no cost to you. Compensation is available for women with children at home, to pay for babysitting services while participating in study visits.
Participants will be eligible for the study if they:
- Are between the ages of 18-45 years old
- Have a diagnosis of Bipolar Disorder, Major Depressive Disorder, or Mood Disorder NOS
- Are planning to become pregnant, or are in the first or second trimester of pregnancy
- Are taking a daily dose of Lamictal (lamotrigine) for mood symptom management
If you are interested in participating or would like to hear more information, please email research coordinator Catalina Montiel or call 855-99-ASHER.