Northwestern University Feinberg School of Medicine
Research

High Impact-Factor Research 2015

Amiram M, Haimovich AD, Fan C, Wang YS, Aerni HR, Ntai I, Moonan DW, Ma NJ, Rovner AJ, Hong SH, Kelleher NL, Goodman AL, Jewett MC, Soll D, Rinehart J, Isaacs FJ. Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids. Nature Biotechnology. 2015 Dec;33(12):1272-1279.

Bonow RO, Nishimura RA, Thompson PD, Udelson JE, Amer Heart A, Amer Coll C. Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 5: Valvular Heart Disease A Scientific Statement From the American Heart Association and American College of Cardiology. Circulation. 2015 Dec;132(22):E292-E297.

Curry MP, O'Leary JG, Bzowej N, Muir AJ, Korenblat KM, Fenkel JM, Reddy KR, Lawitz E, Flamm SL, Schiano T, Teperman L, Fontana R, Schiff E, Fried M, Doehle B, An D, McNally J, Osinusi A, Brainard DM, McHutchison JG, Brown RS, Jr., Charlton M. Sofosbuvir and Velpatasvir for HCV in Patients with Decompensated Cirrhosis. New England Journal of Medicine. 2015 Dec 31;373(27):2618-2628.

Forouzanfar MH, Alexander L, Anderson HR (et al., including Swaroop M, and Yano Y).  Factors GBDR. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Dec;386(10010):2287-2323.

Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Njolstad I, et al. Meta-A DIGR. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics. 2015 Dec;47(12):1415.

Gheorghiade M, Greene SJ, Butler J, Filippatos G, Lam CSP, Maggioni AP, Ponikowski P, Shah SJ, Solomon SD, Kraigher-Krainer E, Samano ET, Muller K, Roessig L, Pieske B, Coo S-RI. Effect of Vericiguat, a Soluble Guanylate Cyclase Stimulator, on Natriuretic Peptide Levels in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction The SOCRATES-REDUCED Randomized Trial. Jama-Journal of the American Medical Association. 2015 Dec;314(21):2251-2262.

Grabner A, Amaral AP, Schramm K, Singh S, Sloan A, Yanucil C, Li JH, Shehadeh LA, Hare JM, David V, Martin A, Fomoni A, Di Marco GS, Kentrup D, Reuter S, Mayer AB, Pavenstadt H, Stypmann J, Kuhn C, Hille S, Frey N, Leifheit-Nestler M, Richter B, Haffner D, Abraham R, Bange J, Sperl B, Ullrich A, Brand M, Wolf M, Faul C. Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy. Cell Metabolism. 2015 Dec;22(6):1020-1032.

Kim S, Ogawa K, Lv J, Schweighofer N, Imamizu H. Neural Substrates Related to Motor Memory with Multiple Timescales in Sensorimotor Adaptation. PLoS Biology. 2015 Dec;13(12):e1002312.

Kong RR, Yi FS, Wen PS, Liu JH, Chen XP, Ren JQ, Li XF, Shang YL, Nie YZ, Wu KC, Fan DM, Zhu L, Feng W, Wu JY.Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression. Journal of Clinical Investigation. 2015 Dec;125(12):4407-4420.

Laramy CR, Brown KA, O'Brien MN, Mirkin CA.High-Throughput, Algorithmic Determination of Nanoparticle Structure from Electron Microscopy Images. ACS Nano. 2015 Dec;9(12):12488-12495.

Liu GL, Zhang C, Wu JS, Mirkin CA.Using Scanning-Probe Block Copolymer Lithography and Electron Microscopy To Track Shape Evolution in Multimetallic Nano clusters. ACS Nano. 2015 Dec;9(12):12137-12145.

Mannix AJ, Zhou XF, Kiraly B, Wood JD, Alducin D, Myers BD, Liu XL, Fisher BL, Santiago U, Guest JR, Yacaman MJ, Ponce A, Oganov AR, Hersam MC, Guisinger NP. Synthesis of borophenes: Anisotropic, two-dimensional boron polymorphs. Science. 2015 Dec;350(6267):1513-1516.

Maron BJ, Udelson JE, Bonow RO, Nishimura RA, Ackerman MJ, Estes NAM, Cooper LT, Link MS, Maron MS, Council Clinical C, Council Cardiovasc Dis Y, Council C, Stroke N, Council Functional G, Tran, Amer Coll C. Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 3: Hypertrophic Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy and Other Cardiomyopathies, and Myocarditis A Scientific Statement From the American Heart Association and American College of Cardiology. Circulation. 2015 Dec;132(22):E273-E280.

Perlman EJ, Gadd S, Arold ST, Radhakrishnan A, Gerhard DS, Jennings L, Huff V, Auvil JMG, Davidsen TM, Dome JS, Meerzaman D, Hsu CH, Nguyen C, Anderson J, Ma Y, Mungall AJ, Moore RA, Marra MA, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Gastier-Foster JM, Ross N, Smith MA. MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours. Nature Communications. 2015 Dec;6.

Pianko S, Flamm SL, Shiffman ML, Kumar S, Strasser SI, Dore GJ, McNally J, Brainard DM, Han LL, Doehle B, Mogalian E, McHutchison JG, Rabinovitz M, Towner WJ, Gane EJ, Stedman CAM, Reddy KR, Roberts SK. Sofosbuvir Plus Velpatasvir Combination Therapy for Treatment-Experienced Patients With Genotype 1 or 3 Hepatitis C Virus Infection A Randomized Trial. Annals of Internal Medicine. 2015 Dec;163(11):11.

Redfield MM, Anstrom KJ, Levine JA, Koepp GA, Borlaug BA, Chen HH, LeWinter MM, Joseph SM, Shah SJ, Semigran MJ, Felker GM, Cole RT, Reeves GR, Tedford RJ, Tang WHW, McNulty SE, Velazquez EJ, Shah MR, Braunwald E, Res NHFC. Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction. New England Journal of Medicine. 2015 Dec;373(24):2314-2324.

Sun SY, Shi GJ, Sha HB, Ji YW, Han XM, Shu X, Ma HM, Inoue T, Gao BX, Kim H, Bu PC, Guber RD, Shen XL, Lee AH, Iwawaki T, Paton AW, Paton JC, Fang DY, Tsai B, Yates JR, Wu HQ, Kersten S, Long QM, Duhamel GE, Simpson KW, Qi L. IRE1 alpha is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nature Cell Biology. 2015 Dec;17(12):1546-1555.

Wen QJ, Yang Q, Goldenson B, Malinge S, Lasho T, Schneider RK, Breyfogle LJ, Schultz R, Gilles L, Koppikar P, Abdel-Wahab O, Pardanani A, Stein B, Gurbuxani S, Mullally A, Levine RL, Tefferi A, Crispino JD.Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition. Nature Medicine. 2015 Dec;21(12):1473.

Wilcox DR, Muller WJ, Longnecker R.HSV targeting of the host phosphatase PP1 alpha is required for disseminated disease in the neonate and contributes to pathogenesis in the brain. Proceedings of the National Academy of Sciences of the United States of America. 2015 Dec;112(50):E6937-E6944.

Baron R, Ferriero DM, Frisoni GB, Bettegowda C, Gokaslan ZL, Kessler JA, Vezzani A, Waxman SG, Jarius S, Wildemann B, Weller M. Neurology-the next 10 years. Nature reviews. Neurology. 2015 2015-Nov;11(11):658-664.

Burridge PW, Sharma A, Wu JC. Genetic and Epigenetic Regulation of Human Cardiac Reprogramming and Differentiation in Regenerative Medicine. Annual Review of Genetics. 2015 Nov 23;49:461-484.

Dou Z, Xu C, Donahue G, Shimi T, Pan J-A, Zhu J, Ivanov A, Capelll BC, Drake AM, Shah PP, Catanzaro JM, Ricketts MD, Lamark T, Adam SA, Marmorstein R, Zong W-X, Johansen T, Goldman RD, Adams PD, Berger SL. Autophagy mediates degradation of nuclear lamina. Nature. 2015 Nov 5;527(7576):105-109.

Falade-Nwulia O, Seaberg EC, Snider AE, Rinaldo CR, Phair J, Witt MD, Thio CL. Incident Hepatitis B Virus Infection in HIV-Infected and HIV-Uninfected Men Who Have Sex With Men From Pre-HAART to HAART Periods A Cohort Study. Annals of Internal Medicine. 2015 Nov;163(9):673.

Gao QQ, Wyatt E, Goldstein JA, LoPresti P, Castillo LM, Gazda A, Petrossian N, Earley JU, Hadhazy M, Barefield DY, Demonbreun AR, Boennemann C, Wolf M, McNally EM. Reengineering a transmembrane protein to treat muscular dystrophy using exon skipping. Journal of Clinical Investigation. 2015 Nov;125(11):4186-4195.

Geier ML, McMorrow JJ, Xu W, Zhu J, Kim CH, Marks TJ, Hersam MC.Solution-processed carbon nanotube thin-film complementary static random access memory. Nature Nanotechnology. 2015 Nov;10(11):944-U191.

Gross JG, Glassman AR, Jampol LM, Inusah S, Aiello LP, Antoszyk AN, Baker CW, Berger BB, Bressler NM, Browning D, Elman MJ, Ferris FL, 3rd, Friedman SM, Marcus DM, Melia M, Stockdale CR, Sun JK, Beck RW. Proliferative Diabetic Retinopathy A Randomized Clinical Trial. JAMA. 2015 2015-Nov-24;314(20):2137-2146.

Hammoud SS, Low DHP, Yi C, Lee CL, Oatley JM, Payne CJ, Carrell DT, Guccione E, Cairns BR. Transcription and imprinting dynamics in developing postnatal male germline stem cells. Genes & Development. 2015 Nov 1;29(21):2312-2324.

Liang K, Woodfin AR, Slaughter BD, Unruh JR, Box AC, Rickels RA, Gao X, Haug JS, Jaspersen SL, Shilatifard A. Mitotic Transcriptional Activation: Clearance of Actively Engaged Pol II via Transcriptional Elongation Control in Mitosis. Molecular Cell. 2015 2015-Nov-5;60(3):435-445.

McLaren PJ, Coulonges C, Bartha I, Lenz TL, Deutsch AJ, Bashirova A, Buchbinder S, Carrington MN, Cossarizza A, Dalmau J, De Luca A, Goedert JJ, Gurdasani D, Haas DW, Herbeck JT, Johnson EO, Kirk GD, Lambotte O, Luo M, Mallal S, van Manen D, Martinez-Picado J, Meyer L, Miro JM, Mullins JI, Obel N, Poli G, Sandhu MS, Schuitemaker H, Shea PR, Theodorou I, Walker BD, Weintrob AC, Winkler CA, Wolinsky SM, Raychaudhuri S, Goldstein DB, Telenti A, de Bakker PIW, Zagury J-F, Fellay J. Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load. Proceedings of the National Academy of Sciences of the United States of America. 2015 2015-Nov-24;112(47):14658-14663.

Miedema MD, Petrone A, Shikany JM, Greenland P, Lewis CE, Pletcher MJ, Gaziano JM, Djousse L. Association of Fruit and Vegetable Consumption During Early Adulthood With the Prevalence of Coronary Artery Calcium After 20 Years of Follow-Up: The Coronary Artery Risk Development in Young Adults (CARDIA) Study. Circulation. 2015 2015-Nov-24;132(21):1990-1998.

Murray CJL, Barber RM, Foreman KJ, Swaroop M,et al. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet. 2015 Nov;386(10009):2145-2191. 

Perelis M, Marcheva B, Ramsey KM, Schipma MJ, Hutchison AL, Taguchi A, Peek CB, Hong H, Huang W, Omura C, Allred AL, Bradfield CA, Dinner AR, Barish GD, Bass J. Pancreatic beta cell enhancers regulate rhythmic transcription of genes controlling insulin secretion. Science. 2015 Nov 6;350(6261):650.

Shen W, Plotkin JL, Francardo V, Ko WKD, Xie Z, Li Q, Fieblinger T, Wess J, Neubig RR, Lindsley CW, Conn PJ, Greengard P, Bezard E, Cenci MA, Surmeier DJ.M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia. Neuron. 2015 2015-Nov-18;88(4):762-773.

Sparano JA, Gray RJ, Makower DF, Pritchard KI, Albain KS, Hayes DF, Geyer CE, Jr., Dees EC, Perez EA, Olson JA, Jr., Zujewski JA, Lively T, Badve SS, Saphner TJ, Wagner LI, Whelan TJ, Ellis MJ, Paik S, Wood WC, Ravdin P, Keane MM, Gomez Moreno HL, Reddy PS, Goggins TF, Mayer IA, Brufsky AM, Toppmeyer DL, Kaklamani VG, Atkins JN, Berenberg JL, Sledge GW. Prospective Validation of a 21-Gene Expression Assay in Breast Cancer. New England Journal of Medicine. 2015 Nov 19;373(21):2005-2014.

Xu W, Hong SJ, Zhong AM, Xie P, Jia SX, Xie Z, Zeitchek M, Niknam-Bienia S, Zhao JL, Porterfield DM, Surmeier DJ, Leung KP, Galiano RD, Mustoe TA.Sodium channel Na-x is a regulator in epithelial sodium homeostasis. Science Translational Medicine. 2015 Nov;7(312):13.

 

Fleshman J, Branda M, Sargent DJ, Boller AM, George V, Abbas M, Peters WR, Jr., Maun D, Chang G, Herline A, Fichera A, Mutch M, Wexner S, Whiteford M, Marks J, Birnbaum E, Margolin D, Larson D, Marcello P, Posner M, Read T, Monson J, Wren SM, Pisters PW, Nelson H. Effect of Laparoscopic-Assisted Resection vs Open Resection of Stage II or III Rectal Cancer on Pathologic Outcomes: The ACOSOG Z6051 Randomized Clinical Trial. JAMA. 2015 Oct 6;314(13):1346-1355.

Gracies JM, Brashear A, Jech R, McAllister P, Banach M, Valkovic P, Walker H, Marciniak C, Deltombe T, Skoromets A, Khatkova S, Edgley S, Gul F, Catus F, De Fer BB, Vilain C, Picaut P, Int Abobotulinumtoxin AAU. Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial. Lancet Neurology. 2015 Oct;14(10):992-1001.

Grijalva CG, Zhu Y, Williams DJ, Self WH, Ampofo K, Pavia AT, Stockmann CR, McCullers J, Arnold SR, Wunderink RG, Anderson EJ, Lindstrom S, Fry AM, Foppa IM, Finelli L, Bramley AM, Jain S, Griffin MR, Edwards KM. Association Between Hospitalization With Community-Acquired Laboratory-Confirmed Influenza Pneumonia and Prior Receipt of Influenza Vaccination. JAMA. 2015 Oct 13;314(14):1488-1497.

Huffmaster NJ, Sollars PJ, Richards AL, Pickard GE, Smith GA. Dynamic ubiquitination drives herpesvirus neuroinvasion. Proceedings of the National Academy of Sciences of the United States of America. 2015 Oct;112(41):12818-12823.

Jovasevic V, Naghavi MH, Walsh D.Microtubule plus end-associated CLIP-170 initiates HSV-1 retrograde transport in primary human cells. Journal of Cell Biology. 2015 Oct 26;211(2):323-337.

Lebwohl M, Strober B, Menter A, Gordon K, Weglowska J, Puig L, Papp K, Spelman L, Toth D, Kerdel F, Armstrong AW, Stingl G, Kimball AB, Bachelez H, Wu JJ, Crowley J, Langley RG, Blicharski T, Paul C, Lacour JP, Tyring S, Kircik L, Chimenti S, Duffin KC, Bagel J, Koo J, Aras G, Li J, Song W, Milmont CE, Shi Y, Erondu N, Klekotka P, Kotzin B, Nirula A. Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis. New England Journal of Medicine. 2015 Oct;373(14):1318-1328.

Li Y, Zhou QL, Sun W, Chandrasekharan P, Cheng HS, Ying Z, Lakshmanan M, Raju A, Tenen DG, Cheng SY, Chuang KH, Li J, Prabhakar S, Li M, Tergaonkar V. Non-canonical NF-kappaB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation. Nature Cell Biology. 2015 Oct;17(10):1327-1338.

Li Z, Hung C, Paterson RG, Michel F, Fuentes S, Place R, Lin Y, Hogan RJ, Lamb RA, He B. Type II integral membrane protein, TM of J paramyxovirus promotes cell-to-cell fusion. Proceedings of the National Academy of Sciences of the United States of America. 2015 Oct 6;112(40):12504-12509.

Moffitt RA, Marayati R, Flate EL, Volmar KE, Loeza SGH, Hoadley KA, Rashid NU, Williams LA, Eaton SC, Chung AH, Smyla JK, Anderson JM, Kim HJ, Bentrem DJ, Talamonti MS, Iacobuzio-Donahue CA, Hollingsworth MA, Yeh JJ. Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma. Nature Genetics. 2015 Oct;47(10):1168-1178.

Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang YW, Zhao CY, Jiang M, Hu DQ, Agirre X, Niesvizky I, Lee JE, Chen HT, Ennishi D, Scott DW, Mottok A, Hother C, Liu SC, Cao XJ, Tam W, Shaknovich R, Garcia BA, Gascoyne RD, Ge K, Shilatifard A, Elemento O, Nussenzweig A, Melnick AM, Wendel HG. The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. Nature Medicine. 2015 Oct;21(10):1199.

Prakriya M, Lewis RS. Store-operated Calcium Channels. Physiological Reviews. 2015 Oct 1;95(4):1383-1436.

Tiacci E, Park JH, De Carolis L, Chung SS, Broccoli A, Scott S, Zaja F, Devlin S, Pulsoni A, Chung YR, Cimminiello M, Kim E, Rossi D, Stone RM, Motta G, Saven A, Varettoni M, Altman JK, Anastasia A, Grever MR, Ambrosetti A, Rai KR, Fraticelli V, Lacouture ME, Carella AM, Levine RL, Leoni P, Rambaldi A, Falzetti F, Ascani S, Capponi M, Martelli MP, Park CY, Pileri SA, Rosen N, Foa R, Berger MF, Zinzani PL, Abdel-Wahab O, Falini B, Tallman MS. Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia. New England Journal of Medicine. 2015 Oct 29;373(18):1733-1747.

Rock CL, Flatt SW, Byers TE, Colditz GA, Demark-Wahnefried W, Ganz PA, Wolin KY, Elias A, Krontiras H, Liu J, Naughton M, Pakiz B, Parker BA, Sedjo RL, Wyatt H. Results of the Exercise and Nutrition to Enhance Recovery and Good Health for You (ENERGY) Trial: A Behavioral Weight Loss Intervention in Overweight or Obese Breast Cancer Survivors. Journal of Clinical Oncology. 2015 Oct 1;33(28):3169-3176.

Roth GA, Huffman MD, Moran AE, Feigin V, Mensah GA, Naghavi M, Murray CJ. Global and Regional Patterns in Cardiovascular Mortality From 1990 to 2013. Circulation. 2015 Oct 27;132(17):1667-1678.

Silverberg MJ, Lau B, Achenbach CJ, Jing YZ, Althoff KN, D'Souza G, Engels EA, Hessol NA, Brooks JT, Burchell AN, Gill MJ, Goedert JJ, Hogg R, Horberg MA, Kirk GD, Kitahata MM, Korthuis PT, Mathews WC, Mayor A, Modur SP, Napravnik S, Novak RM, Patel P, Rachlis AR, Sterling TR, Willig JH, Justice AC, Moore RD, Dubrow R, Int Epidemiologic D. Cumulative Incidence of Cancer Among Persons With HIV in North America A Cohort Study. Annals of Internal Medicine. 2015 Oct;163(7):507.

Weber EW, Han F, Tauseef M, Birnbaumer L, Mehta D, Muller WA. TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response. Journal of Experimental Medicine. 2015 Oct 19;212(11):1883-1899.

Zhang Y, Rajan R, Seifert HS, Mondragon A, Sontheimer EJ. DNase H Activity of Neisseria meningitidis Cas9. Molecular Cell. 2015 Oct 15;60(2):242-255.

 

Ackermann RT. Diabetes Prevention at the Tipping Point: Aligning Clinical and Public Health Recommendations. Annals of Internal Medicine. 2015 Sep;163(6):475-476.

Biswas KH, Hartman KL, Yu CH, Harrison OJ, Song H, Smith AW, Huang WYC, Lin WC, Guo ZH, Padmanabhan A, Troyanovsky SM, Dustin ML, Shapiro L, Honig B, Zaidel-Bar R, Groves JT. E-cadherin junction formation involves an active kinetic nucleation process. Proceedings of the National Academy of Sciences of the United States of America. 2015 Sep;112(35):10932-10937.

Burton BK, Balwani M, Feillet F, Baric I, Burrow TA, Grande CC, Coker M, Consuelo-Sanchez A, Deegan P, Di Rocco M, Enns GM, Erbe R, Ezgu F, Ficicioglu C, Furuya KN, Kane J, Laukaitis C, Mengel E, Neilan EG, Nightingale S, Peters H, Scarpa M, Schwab KO, Smolka V, Valayannopoulos V, Wood M, Goodman Z, Yang Y, Eckert S, Rojas-Caro S, Quinn AG. A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency. New England Journal of Medicine. 2015 Sep;373(11):1010-1020.

Havranek EP, Mujahid MS, Barr DA, Blair IV, Cohen MS, Cruz-Flores S, Davey-Smith G, Dennison-Himmelfarb CR, Lauer MS, Lockwood DW, Rosal M, Yancy CW, Amer Heart Assoc Council Q, Council Epidemiology P, Council Cardiovasc Stroke N, Council Lifestyle Cardiometab H, Stroke C. Social Determinants of Risk and Outcomes for Cardiovascular Disease A Scientific Statement From the American Heart Association. Circulation. 2015 Sep;132(9):873-898.

Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang HH, Wang TFA, Stehbens SJ, Younger S, Barshow S, Zhu SJ, Cooper MK, Peacock J, Ramaswamy V, Garzia L, Wu XC, Remke M, Forester CM, Kim CC, Weiss WA, James CD, Shuman MA, Bader GD, Mueller S, Taylor MD, Jan YN, Jan LY. EAG2 potassium channel with evolutionarily conserved function as a brain tumor target. Nature Neuroscience. 2015 Sep;18(9):1236.

Jovasevic V, Corcoran KA, Leaderbrand K, Yamawaki N, Guedea AL, Chen HJ, Shepherd GMG, Radulovic J.GABAergic mechanisms regulated by miR-33 encode state-dependent fear. Nature Neuroscience. 2015 Sep;18(9):1265.

Lim K, Hyun YM, Lambert-Emo K, Capece T, Bae S, Miller R, Topham DJ, Kim M. Neutrophil trails guide influenza-specific CD8(+) T cells in the airways. Science. 2015 Sep;349(6252):1071.

Minami CA, Yang AD, Szmuilowicz E.Negotiating the Tensions in Patient-Centered Care. Jama-Journal of the American Medical Association. 2015 Sep;314(11):1167-1168.

Sandhu A, McCoy LA, Negi SI, Hameed I, Atri P, Al'Aref SJ, Curtis J, McNulty E, Anderson HV, Shroff A, Menegus M, Swaminathan RV, Gurm H, Messenger J, Wang T, Bradley SM. Use of Mechanical Circulatory Support in Patients Undergoing Percutaneous Coronary Intervention: Insights From the National Cardiovascular Data Registry. Circulation. 2015 Sep 29;132(13):1243-1251.

Wunderink RG.CAP death: what goes wrong when everything is right?Lancet Infectious Diseases. 2015 Sep;15(9):995-996.

Yeboah J, Polonsky TS, Young R, McClelland RL, Delaney JC, Dawood F, Blaha MJ, Miedema MD, Sibley CT, Carr JJ, Burke GL, Goff DC, Psaty BM, Greenland P, Herrington DM. Utility of Nontraditional Risk Markers in Individuals Ineligible for Statin Therapy According to the 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines. Circulation. 2015 Sep;132(10):916-922.

Zhu JJ, Sammons MA, Donahue G, Dou ZX, Vedadi M, Getlik M, Barsyte-Lovejoy D, Al-Awar R, Katona BW, Shilatifard A, Huang J, Hua XX, Arrowsmith CH, Berger SL. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth. Nature. 2015 Sep;525(7568):206.

Baliki MN, Apkarian AV. Nociception, Pain, Negative Moods, and Behavior Selection. Neuron. 2015 Aug 5;87(3):474-491.

Belfort MA, Saade GR, Thom E, Blackwell SC, Reddy UM, Thorp JM, Jr., Tita AT, Miller RS, Peaceman AM, McKenna DS, Chien EK, Rouse DJ, Gibbs RS, El-Sayed YY, Sorokin Y, Caritis SN, VanDorsten JP. A Randomized Trial of Intrapartum Fetal ECG ST-Segment Analysis. New England Journal of Medicine. 2015 Aug 13;373(7):632-641.

Briley WE, Bondy MH, Randeria PS, Dupper TJ, Mirkin CA. Quantification and real-time tracking of RNA in live cells using Sticky-flares. Proceedings of the National Academy of Sciences of the United States of America. 2015 Aug;112(31):9591-9595.

Campbell EM, Hope TJ. HIV-1 capsid: the multifaceted key player in HIV-1 infection. Nature Reviews Microbiology. 2015 Aug;13(8):471-483.

Chen CS, Hong S, Indra I, Sergeeva AP, Troyanovsky RB, Shapiro L, Honig B, Troyanovsky SM. alpha-Catenin-mediated cadherin clustering couples cadherin and actin dynamics. Journal of Cell Biology. 2015 Aug 17;210(4):647-661.

Chen FX, Woodfin AR, Gardini A, Rickels RA, Marshall SA, Smith ER, Shiekhattar R, Shilatifard A. PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II. Cell. 2015 Aug 27;162(5):1003-1015.

Christine PJ, Auchincloss AH, Bertoni AG, Carnethon MR, Sanchez BN, Moore K, Adar SD, Horwich TB, Watson KE, Diez Roux AV. Longitudinal Associations Between Neighborhood Physical and Social Environments and Incident Type 2 Diabetes Mellitus: The Multi-Ethnic Study of Atherosclerosis (MESA). JAMA Intern Med. 2015 Aug 1;175(8):1311-1320.

Coleman KE, Grant GD, Haggerty RA, Brantley K, Shibata E, Workman BD, Dutta A, Varma D, Purvis JE, Cook JG. Sequential replication-coupled destruction at G1/S ensures genome stability. GenesDevelopment. 2015 Aug 15;29(16):1734-1746.

Contractor A, Klyachko VA, Portera-Cailliau C. Altered Neuronal and Circuit Excitability in Fragile X Syndrome. Neuron. 2015 Aug 19;87(4):699-715.

Davies MJ, Bergenstal R, Bode B, Kushner RF, Lewin A, Skjoth TV, Andreasen AH, Jensen CB, DeFronzo RA. Efficacy of Liraglutide for Weight Loss Among Patients With Type 2 Diabetes: The SCALE Diabetes Randomized Clinical Trial. JAMA. 2015 Aug 18;314(7):687-699.

de Almeida L, Khare S, Misharin AV, Patel R, Ratsimandresy RA, Wallin MC, Perlman H, Greaves DR, Hoffman HM, Dorfleutner A, Stehlik C.The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease. Immunity. 2015 Aug 18;43(2):264-276.

Feltes TF, Roth SJ, Almodovar MC, Andropoulos DB, Bohn DJ, Costello JM, Gajarski RJ, Mott AR, Koenig P.Task Force 5: Pediatric Cardiology Fellowship Training in Critical Care Cardiology. Circulation. 2015 Aug 11;132(6):e81-90.

Flourakis M, Kula-Eversole E, Hutchison AL, Han TH, Aranda K, Moose DL, White KP, Dinner AR, Lear BC, Ren D, Diekman CO, Raman IM, Allada R.A Conserved Bicycle Model for Circadian Clock Control of Membrane Excitability. Cell. 2015 Aug 13;162(4):836-848.

Freud LR, Escobar-Diaz MC, Kalish BT, Komarlu R, Puchalski MD, Jaeggi ET, Szwast AL, Freire G, Levasseur SM, Kavanaugh-McHugh A, Michelfelder EC, Moon-Grady AJ, Donofrio MT, Howley LW, Tierney ES, Cuneo BF, Morris SA, Pruetz JD, van der Velde ME, Kovalchin JP, Ikemba CM, Vernon MM, Samai C, Satou GM, Gotteiner NL, Phoon CK, Silverman NH, McElhinney DB, Tworetzky W. Outcomes and Predictors of Perinatal Mortality in Fetuses With Ebstein Anomaly or Tricuspid Valve Dysplasia in the Current Era: A Multicenter Study. Circulation. 2015 Aug 11;132(6):481-489.

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Wainwright CE, Elborn JS, Ramsey BW, Marigowda G, Huang X, Cipolli M, Colombo C, Davies JC, De Boeck K, Flume PA, Konstan MW, McColley SA, McCoy K, McKone EF, Munck A, Ratjen F, Rowe SM, Waltz D, Boyle MP, Grp TS, Grp TS. Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR. New England Journal of Medicine. 2015 Jul;373(3):220-231.

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Antic I, Biancucci M, Zhu Y, Gius DR, Satchell KJ. Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain. Nature Communications. 2015 Jun 8;6:7396. 

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Wong YL, Anzola JV, Davis RL, Yoon M, Motamedi A, Kroll A, Seo CP, Hsia JE, Kim SK, Mitchell JW, Mitchell BJ, Desai A, Gahman TC, Shiau AK, Oegema K. Cell biology: Reversible centriole depletion with an inhibitor of Polo-like kinase 4. Science. 2015 Jun 5;348(6239):1155-60. 

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Johnson ML, Yu HA, Hart EM, Weitner BB, Rademaker AW, Patel JD, Kris MG, Riely GJ. Phase I/II Study of HSP90 Inhibitor AUY922 and Erlotinib for EGFR-Mutant Lung Cancer With Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. Journal of Clinical Oncology. 2015 May;33(15):1666-+.

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Madara JL, Burkhart J. Professionalism, self-regulation, and motivation: How did health care get this so wrong?JAMA -Journal of the American Medical Association. 2015;313(18):1793-1794.

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Pandolfino JE, Gawron AJ. Achalasia: a systematic review. JAMA- Journal of the American Medical Association. 2015 May 12;313(18):1841-52. 

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Zhang Q, Kuang H, Chen C, Yan J, Do-Umehara HC, Liu XY, Dada L, Ridge KM, Chandel NS, Liu J. The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation. Nature Immunology. 2015 May;16(5):458-66. 

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Bharat A, Cunningham SA, Scott Budinger GR, Kreisel D, DeWet CJ, Gelman AE, Waites K, Crabb D, Xiao L, Bhorade S, Ambalavanan N, Dilling DF, Lowery EM, Astor T, Hachem R, Krupnick AS, DeCamp MM, Ison MG, Patel R. Disseminated Ureaplasma infection as a cause of fatal hyperammonemia in humans. Science Translational Medicine. 2015 Apr 22;7(284):284re3. 

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Elliott P, Posma JM, Chan Q, Garcia-Perez I, Wijeyesekera A, Bictash M, D Ebbels TM, Ueshima H, Zhao L, van Horn L, Daviglus M, Stamler J, Holmes E, Nicholson JK. Urinary metabolic signatures of human adiposity. Science Translational Medicine. 2015 Apr 29;7(285):285ra62. 

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Jang KI, Chung HU, Xu S, Lee CH, Luan HW, Jeong J, Cheng HY, Kim GT, Han SY, Lee JW, Kim J, Cho M, Miao FX, Yang YY, Jung HN, Flavin M, Liu H, Kong GW, Yu KJ, Rhee SI, Chung J, Kim B, Kwak JW, Yun MH, Kim JY, Song YM, Paik U, Zhang YH, Huang Y, Rogers JA. Soft network composite materials with deterministic and bio-inspired designs. Nature Communications. 2015 Mar;6.

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Reissfelder C, Stamova S, Gossmann C, Braun M, Bonertz A, Walliczek U, Grimm M, Rahbari NN, Koch M, Saadati M, Benner A, Bchler MW, Jger D, Halama N, Khazaie K, Weitz J, Beckhove P. Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis. Journal of Clinical Investigation. 2015 Mar 2;125(3):1364.

Rotz MW, Culver KSB, Parigi G, MacRenaris KW, Luchinat C, Odom TW, Meade TJ. High Relaxivity Gd(III) - DNA Gold Nanostars: Investigation of Shape Effects on Proton Relaxation. ACS Nano. 2015 Mar;9(3):3385-3396.

Wagner LI, Zhao FM, Hong FX, Williams ME, Gascoyne RD, Krauss JC, Advani RH, Go RS, Habermann TM, Leach JW, O'Connor B, Schuster SJ, Cella D, Horning SJ, Kahl BS. Anxiety and Health-Related Quality of Life Among Patients With Low-Tumor Burden Non-Hodgkin Lymphoma Randomly Assigned to Two Different Rituximab Dosing Regimens: Results From ECOG Trial E4402 (RESORT). Journal of Clinical Oncology. 2015 Mar;33(7).

Wang X, Duch MC, Mansukhani N, Ji ZX, Liao YP, Wang MY, Zhang HY, Sun BB, Chang CH, Li RB, Lin SJ, Meng H, Xia T, Hersam MC, Nel AE. Use of a Pro-Fibrogenic Mechanism-Based Predictive Toxicological Approach for Tiered Testing and Decision Analysis of Carbonaceous Nanomaterials. ACS Nano. 2015 Mar;9(3):3032-3043.

Way SW, Podojil JR, Clayton BL, Zaremba A, Collins TL, Kunjamma RB, Robinson AP, Brugarolas P, Miller RH, Miller SD, Popko B. Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic. Nature Communications. 2015 Mar;6.

Weinberg SE, Sena LA, Chandel NS. Mitochondria in the Regulation of Innate and Adaptive Immunity. Immunity. 2015 Mar 17;42(3):406-417.

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Harris KD, Shepherd GM. The neocortical circuit: themes and variations. Nature Neuroscience. 2015 Feb;18(2):170-181.

Hong XM, Hao K, Ladd-Acosta C, Hansen KD, Tsai HJ, Liu X, Xu X, Thornton TA, Caruso D, Keet CA, Sun YF, Wang GY, Luo W, Kumar R, Fuleihan R, Singh AM, Kim JS, Story RE, Gupta RS, Gao PS, Chen Z, Walker SO, Bartell TR, Beaty TH, Fallin MD, Schleimer R, Holt PG, Nadeau KC, Wood RA, Pongracic JA, Weeks DE, Wang XB. Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Nature Communications. 2015 Feb;6.

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Luo Z, Gao X, Lin C, Smith ER, Marshall SA, Swanson SK, Florens L, Washburn MP, Shilatifard A.Zic2 is an enhancer-binding factor required for embryonic stem cell specification. Molecular Cell. 2015 Feb 19;57(4):685-94. 

McNally EM, Barefield DY, Puckelwart MJ. The Genetic Landscape of Cardiomyopathy and Its Role in Heart Failure. Cell Metabolism. 2015 Feb 3;21(2):174-182.

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Merkow RP, Ju MH, Chung JW, Hall BL, Cohen ME, Williams MV, Tsai TC, Ko CY, Bilimoria KY. Underlying reasons associated with hospital readmission following surgery in the United States. JAMA- Journal of the American Medical Association. 2015 Feb 3;313(5):483-95. 

Morgan MA, Shilatifard A. Chromatin signatures of cancer. Genes & Development. 2015 Feb 1;29(3):238-249.

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Walz AL et al.(including Gadd S, Jafari N and Perlman EJ). Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors. Cancer Cell. 2015 Feb 9;27(2):286-97. 

Wasserman M, Zeng XHT, Amaral LAN.Cross-evaluation of metrics to estimate the significance of creative worksProceedings of the National Academy of Sciences. U.S.A. 2015;112(5):1281-1286.

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Burt RK, Balabanov R, Han X, Sharrack B, Morgan A, Quigley K, Yaung K, Helenowski IB, Jovanovic B, Spahovic D, Arnautovic I, Lee DC, Benefield BC, Futterer S, Oliveira MC, Burman J. Association of nonmyeloablative hematopoietic stem cell transplantation with neurological disability in patients with relapsing-remitting multiple sclerosis. JAMA - Journal of the American Medical Association. 2015;313(3):275-284.

Chen F, Gao X, Shilatifard A. Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide. Genes & Development. 2015 Jan 1;29(1):39-47. 

Chu HY, Atherton JF, Wokosin D, Surmeier DJ, Bevan MD.Heterosynaptic regulation of external globus pallidus inputs to the subthalamic nucleus by the motor cortex. Neuron. 2015 Jan 21;85(2):364-76.

Kershaw KN, Osypuk TL, Do DP, De Chavez PJ, Roux AVD. Neighborhood-Level Racial/Ethnic Residential Segregation and Incident Cardiovascular Disease The Multi-Ethnic Study of Atherosclerosis. Circulation. 2015 Jan;131(2):141-U159.

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Pfeffer MA, Claggett B, Assmann SF, Boineau R, Anand IS, Clausell N, Desai AS, Diaz R, Fleg JL, Gordeev I, Heitner JF, Lewis EF, O'Meara E, Rouleau JL, Probstfield JL, Shaburishvili T, Shah SJ, Solomon SD, Sweitzer NK, McKinlay SM, Pitt B. Regional variation in patients and outcomes in the treatment of preserved cardiac function heart failure with an aldosterone antagonist (TOPCAT) trial. Circulation. 2015;131(1):34-42.

Schneider C, Smith DF, Cummings RD, Boligan KF, Hamilton RG, Bochner BS, Miescher S, Simon HU, Pashov A, Vassilev T, Von Gunten S. The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Science Translational Medicine. 2015;7(269).

Shah SJ, Katz DH, Selvaraj S, Burke MA, Yancy CW, Gheorghiade M, Bonow RO, Huang CC, Deo RC. Phenomapping for novel classification of heart failure with preserved ejection fraction. Circulation. 2015;131(3):269-279.

Viola KL, Sbarboro J, Sureka R, De M, Bicca MA, Wang J, Vasavada S, Satpathy S, Wu S, Joshi H, Velasco PT, MacRenaris K, Waters EA, Lu C, Phan J, Lacor P, Prasad P, Dravid VP, Klein WL. Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease. Nature Nanotechnology. 2015 Jan;10(1):91-8.

Weinberg SE, Chandel NS. Targeting mitochondria metabolism for cancer therapy. Nature Chemistry Biology. 2015 Jan;11(1):9-15.

Wessel J et al. (including Rasmussen-Torvik LJ and BaldridgeAS) Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications. 2015 Jan;6.

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Zhang P, Chaturvedi CP, Tremblay V, Cramet M, Brunzelle JS, Skiniotis G, Brand M, Shilatifard A, Couture JF. A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation. Genes & Development. 2015 Jan 15;29(2):123-8.