Northwestern University Feinberg School of Medicine

Center for Advanced Microscopy


The Center for Advanced Microscopy (CAM) offers state-of-the art instrumentation and services for the study of biological processes at the whole animal, tissue, cellular, and subcellular levels. The center’s services include confocal microscopy, multiphoton imaging, super-resolution microscopy (SIM & STORM), fluorescence lifetime imaging, anisotropy imaging, fluorescence correlation spectroscopy imaging, microinjection, laser microdissection, whole animal bioluminescent and fluorescent imaging, transmission electron microscopy, platinum replica electron microscopy, and 3D tomography. Many of our scopes come equipped with temperature, CO2, and humidity controlled chambers for live cell observation. We also will consult on computerized image analysis, and digital image manipulation.

Services Offered

  • Training and technical support for intravital, light and electron microscopy
  • Preparation of samples for light or electron microscopy

Equipment Available

The Center for Advanced Microscopy is located on the second floors of the adjoining Searle and Morton buildings. It consists of a 16-room suite that occupies approximately 3,950 sf. Within the facility, there are two "wet" laboratory rooms with fume hoods, one specifically for EM sample preparation, and one available for users who need immediate laboratory set-up to complete their time-dependent imaging experiments.

  • Light Microscopy
    • Andor XDI Revolution Spinning Disk Confocal Microscope
    • CRI Nuance Spectral Imaging Microscope
    • ISS Alba Lifetime, FCS, Anistropy Imaging Microscope
    • IVIS Spectrum Imaging System
    • Nikon AZ-100 Multi-purpose Zoom Microscope
    • Nikon A1R Laser Scanning Confocal Microscopes (2)
    • Nikon Biostation IM-Q Live Cell Imaging Microscopes (2)
    • Nikon C2 Laser Scanning Confocal Microscope
    • Nikon Multiphoton Microscope
    • Nikon N-SIM Structured Illumination Super-resolution Microscope
    • Nikon STochastic Optical Reconstruction Microscope (STORM)
    • Olympus DSU with Eppendorf Femtojet Microinjector
    • TissueGnostics Tissue Cytometer
    • Zeiss PALM Laser Catapulting Microdissection System
    • ZeissUV LSM 510 META Laser Scanning Confocal Microscope
  • Electron Microscopy
    • Bal-Tec Med 020 Coating System
    • Dissecting and light microscopes
    • Protein spray apparatus
    • Tousimis Samdri 790 critical point dyer
    • Ovens for curing resin blocks
    • Leica EM Automatic Freeze Substitution System
    • Leica Ultracut UCT ultramicrotome
    • One LKB 7800 knife maker
    • FEI Tecnai Spirit G2 transmission electron microscope with 3D tomography capability
    • Leica EM CPC plunge freezer
    • BOC Edwards Auto 360 coater


All manuscripts and grants presenting work supported by this core should include the following acknowledgement:

"This work was supported by Northwestern University's Center for Advanced Microscopy and a Cancer Center Support Grant (NCI CA060553)."


CAM Home Page

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Joshua Rappoport, PhD  
(312) 503-4140


Searle/Mortion 2nd Floor
303 E. Chicago Avenue
Chicago, IL  60611