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Hayashida T, Wu M-H, Pierce A, Poncelet AC, Varga J, Schnaper HE: MAP kinase activity necessary for TGF-β1-stimulated mesangial cell type I collagen expression requires adhesion-dependent phosphorylation of FAK tyrosine 397.  J Cell Sci, 120: 4230-4240, 2007.  Click here to link to publication

Okano K, Schnaper HW, Bomsztyk K, Hayashida T: RACK1 minds to Smad3 to modulate TGF-β1-stimulated Éα2(I) collagen transcription in renal tubular epithelial cells. J Biol Chem 281: 26196-26204, 2006.  Click here to link to publication. 

Schnaper HW, Kopp JB: Why kidneys fail: report from an American Society of Nephrology Advances in Research Conference.  J Am Soc Nephrol, 17:1777-1781, 2006. http://jasn.asnjournals.org/cgi/content/short/ASN.2006030267v1

Runyan CE, Schnaper HW, Poncelet A-C:  The role of internalization in TGF-β-induced Smad2 association with SARA and Smad2-dependent signaling in human mesangial cells. J Biol Chem 280: 8300-8308, 2005. http://www.jbc.org/cgi/content/full/280/9/8300

Ingelfinger JR, Schnaper HW. Renal endowment: developmental origins of adult disease. J Am Soc Nephrol 16: 2533-2536, 2005. http://jasn.asnjournals.org/cgi/content/full/16/9/2533

Groten T, Pierce A, Huen A, Schnaper HW:  17β-estradiol transiently disrupts adherens junctions in endothelial cells via Src family kinases. FASEB J. 19:1368-1370, 2005 [Epub ahead of print 2005; 10.1096/fj.04-2558fje] http://www.fasebj.org/cgi/content/short/19/10/1368

Schnaper HW:  Renal fibrosis:  an overview.  In Varga J, Brenner DA, Phan SH (eds): Fibrosis Research: Methods and Protocols.  Totowa, NJ: Humana Press., 2005, pp. 45-68.

Runyan CE, Schnaper HW, Poncelet A-C:  The phosphatidylinositol 3-kinase/Akt pathway enhances Smad3-stimulated mesangial cell collagen I expression in response to transforming growth factor-β1.  J. Biol Chem 279: 2632-2639, 2004. http://www.jbc.org/cgi/content/short/M310412200v1

Hayashida T, Schnaper HW:  High ambient glucose enhances sensitivity to TGF-β1 via ERK and PKCδ in human mesangial cells.  J Am Soc Nephrol, 15: 2032-2041, 2004.  Hubchak SC, Runyan CE, Kreisberg JI, Schnaper HW. Cytoskeletal rearrangement and signal transduction in TGF-beta1-stimulated mesangial cell collagen accumulation. J Am Soc Nephrol. 2003 Aug;14(8):1969-80. PMID: 12874450 http://www.jasn.org/cgi/content/full/14/8/1969

Hayashida T, Decaestecker M, Schnaper HW. Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells. FASEB J. 2003 Aug;17(11):1576-8. Epub 2003 Jun 17. PMID: 12824291 http://www.fasebj.org/cgi/content/full/17/11/1576

Runyan CE, Schnaper HW, Poncelet AC. Smad3 and PKCdelta mediate TGF-beta1-induced collagen I expression in human mesangial cells. Am J Physiol Renal Physiol. 2003 Sep;285(3):F413-22. Epub 2003 May 20. PMID: 12759229 http://ajprenal.physiology.org/cgi/content/full/285/3/F413

Schnaper HW. Idiopathic focal segmental glomerulosclerosis. Semin Nephrol. 2003 Mar;23(2):183-93. Review. PMID: 12704578

Schnaper HW, Hayashida T, Hubchak SC, Poncelet AC. TGF-beta signal transduction and mesangial cell fibrogenesis. Am J Physiol Renal Physiol. 2003 Feb;284(2):F243-52. Review. PMID: 12529270 http://ajprenal.physiology.org/cgi/content/full/284/2/F243

Schnaper HW, Kopp JB. Renal fibrosis. Front Biosci. 2003 Jan 1;8:e68-86. PMID: 12456333 (online journal)

Palfrey BA, Basu R, Frederick KK, Entsch B, Ballou DP.  Role of protein flexibility in the catalyti cycle of p-hydroxybenzoate hydroxylase elucidated by the Pro293Ser mutant.  Biochemistry 2002 Jul;41(26)8438-46.http://pubs.acs.org/cgi-bin/article.cgi/bichaw/2002/41/i26/html/bi012073g.html

Schnaper HW, Hayashida T, Poncelet AC. It's a Smad world: regulation of TGF-beta signaling in the kidney. J Am Soc Nephrol. 2002 Apr;13(4):1126-8. Editorial. PMID: 11912276 http://www.jasn.org/cgi/content/full/13/4/1126

Liao, X., Anjaneyulu, P.S.R., Curley, J. F. Hsu, M., Piccirilli, J. A. The tetrahymena ribozyme cleaves a 5’- methylene phosphonate monoester ~102 fold faster than a normal phosphate diester: Implications for enzyme catalysis of phosphoryl transfer reactions.Biochemistry 2001, 40, 10911. http://pubs.acs.org/cgi-bin/article.cgi/bichaw/2001/40/i37/html/bi010801u.html

Poncelet AC, Schnaper HW. Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cells. J Biol Chem. 2001 Mar 9;276(10):6983-92. Epub 2000 Dec 12. Erratum in: J Biol Chem 2001 Dec 14;276(50):47746. PMID: 11114293 http://www.jbc.org/cgi/content/full/276/10/6983

Hayashida T, Poncelet AC, Hubchak SC, Schnaper HW. TGF-beta1 activates MAP kinase in human mesangial cells: a possible role in collagen expression. Kidney Int. 1999 Nov;56(5):1710-20. PMID: 10571779 http://www.blackwell-synergy.com/links/doi/10.1046/j.1523-1755.1999.00733.x/full/

Poncelet AC, de Caestecker MP, Schnaper HW. The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells. Kidney Int. 1999 Oct;56(4):1354-65. PMID: 10504488 http://www.blackwell-synergy.com/links/doi/10.1046/j.1523-1755.1999.00680.x/full/

Curley, J. F., Joyce, C. M., and Piccirilli, J. A. Functional evidence that the 3’-5’ exonuclease domain of Escherichia coli DNA polymerase I employs a divalent metal ion in leaving group stabilization. J Am Chem Soc 1997, 119, 12691. http://pubs.acs.org.turing.library.northwestern.edu/cgi-bin/article.cgi/jacsat/1997/119/i51/html/ja972014j.html

Kolel-Veetil, M. K., Curley, J. F., Yadav,P. R., Ahmed, K. J. The x-ray structure and substitution reactions of the amido bridged irII dimer Ir2(I)2[m-NH(p-tolyl)]2(CO)4.Polyhedron 1994, 13, 919.  Click here to link to publication.

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