| Outcomes science, epidemiology and clinical trials The study of outcomes of neurosurgical intervention, including relevant parameters for assessing the impact of neurosurgical diseases on quality of life, the safety and effectiveness of novel therapies, and optimal models of their delivery and integration in health care. Technology development and assessment The development of novel technologies for the diagnosis and treatment of neurosurgical diseases. These include molecular imaging and therapeutic vector delivery to the brain and spine, modulation of neurologic function, and technical enhancements of neurosurgical treatments through computer applications, robotics, nanotechnology and minimally invasive strategies. The scientific assessment of the safety and effectiveness of novel technologies Basic mechanisms of neurosurgical diseases The study of systems biology, cellular, genetic and molecular mechanisms associated with neurosurgical diseases. The applications of mechanistic concepts for explaining, predicting and modifying disease behavior.
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