MOLECULAR BIOLOGY
and GENETICS

Faculty Research Interests

Molecular Biology of the Cell    Gene Expression, Replication and Recombination

Nanotechnology    Signal Transduction

Development and Morphogenesis

  
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    Molecular Biology of the Cell
Hossein Ardehali, MD, PhD Role of mitochondria in ischemic heart disease and cell death
Daniel Batlle MD Cellular Defects in Hypertension and Diabetes
David Engman, MD, PhD Molecular genetics and cell biology of tropical parasites
Vladimir Gelfand, PhD Cytoskeleton, microtubules, and intracellular transport
Cara Gottardi, PhD Roles for catenins and cadherins in cell adhesion
Thomas Hope, PhD Viral Posttranscriptional Regulatory Elements
Sui Huang, PhD Function of perinucleolar compartment in cancer cells
Peter Kopp, MD Molecular genetics of thyroid and other endocrine disorders
Steven Kosak, PhD Nuclear Form and Function during Cellular Differentiation and Disease
Liming Li, PhD Structural properties of prion proteins
William Lowe, Jr., MD Diabetes, Vascular Cells and Genetics
Sarah Rice, PhD Functions of molecular motor tails
Jacob Sznajder, MD Mediators and mechanisms of acute lung injury - regulation of Na,K-ATPase in the alveolar epithelium
Sergey M. Troyanovsky, PhD Assembly of cell-cell adhesion structures
    Gene Expression, Replication and Recombination of DNA
Michael Abecassis, MD Cytomegalovirus latency and reactivation
Debabrata Chakravarti, PhD Regulations of cancer cell function, hormone signaling and chromatin modifications
Chonghui Cheng, MD, PhD Alternative splicing in cancer development
Nicholas Cianciotto, PhD Pathogenesis of Legionella pneumophila, agent of Legionnaires' Disease
John Crispino, PhD Transcriptional regulation of normal and malignant blood cell development
Elizabeth Eklund, MD Molecular biology of late myeloid differentiation
Deyu Fang, PhD Molecular networks in the regulation of immune response and autoimmunity
Ann Harris, PhD Chromatin Structure and the Regulation of Gene Expression; Pancreas Cancer
Laura Herzing, PhD Epigenetic control of gene expression in neurodevelopmental, psychiatric and seizure disorders
Byung Kim, PhD Immune mechanisms of autoimmunity and virus-induced demyelination
J. Julie Kim, PhD Molecular events in the endometrium during early pregnancy, endometriosis and endometrial cancer
Lou Laimins, PhD Human papillomaviruses and cervical cancer
Wyndham Lathem, PhD Post-transcriptional regulatory networks in Yersinia
Jonathan Leis, PhD Replication of Retroviruses
Jonathan Licht, MD Transcription factors disrupted in human cancer - Mechanism of action and targets
Richard Longnecker, PhD Epstein-Barr virus transformation, latency, and entry
Vijay Sarthy, PhD Gene regulation, development and functional organization of the vertebrate retina
Richard Scarpulla, PhD Transcriptional mechanisms of nucleo-mitochondrial interaction in mammalian cells
Hank Seifert, PhD Molecular mechanisms of pilus antigenic variation in Neisseria gonorrhoeae
Marcelo Soares, PhD Genomic instability, aberrant transcription and splicing in cancer
Tom Volpe, PhD Heterochromatin formation in eukaryotes
Gayle Woloschak, PhD Nanocomposites; Genes controlling radiosensitivity and motor neuron dysfunction
Jane Wu, MD, PhD Pre-mRNA splicing defects in neurodegenerative disorders; molecular mechanisms of cell migration
Jindan Yu, MD, PhD Genetic and epigenetic pathways to prostate cancer
Liang Zhou, PhD Roles for transcription factors in Th17 and Treg lineage determination
    Nanotechnology
C. Shad Thaxton, MD, PhD Translational nanotechnology
Gayle Woloschak, PhD Nanocomposites; Genes controlling radiosensitivity and motor neuron dysfunction
    Signal Transduction
Markus Bredel, MD, PhD Modulating the NF-kB Pathway in Human Tumors
Paul Bryce, PhD Roles for histamine in immune sensitization and allergy
Irina V. Budunova, MD, PhD Cell signaling and intercellular communications in skin tumorigenesis and development
Charles Clevenger, MD, PhD Prolactin receptor in breast cancer and mammary gland development
Joan Cook-Mills, PhD VCAM-1 and endothelial cell intracellular signals
Seth Corey, MD, MPH Role of Src family protein kinases in proliferation and cytoskeletal reorganization
Xiaolin He, PhD Structural mechanisms of transmembrane signaling events in cancer and neural growth
Jaime García-Añoveros, PhD Genetic dissection of hearing, touch and pain in mammals and in the nematode Caenorhabditis elegans
Spiro Getsios, PhD Cell-cell adhesion and communication in development and disease
Richard Green, MD Molecular mechanisms and genetics of non-alcoholic fatty liver disorders
Kouichi Iwasaki, PhD Molecular biology and genetics of a rhythmic behavior
Jacqueline S. Jeruss, MD, PhD Signaling in Breast Cancer: Disease Development and Progression
Geoffrey Kansas, PhD Molecular biology of leukocyte adhesion and migration
William Karpus, PhD The role of chemokines and cytokines in autoimmunity
Raj Kishore, PhD Roles of inflammatory cytokines, stem cells, and alcohol consumption in heart disease
Douglas A. Kuperman, PhD Mechanisms of asthma pathogenesis
Jing Liu, PhD Signaling by JNK and NF-kB in cell death, inflammation and tumorigenesis
Nick Lu, PhD Glucocorticoid receptor in asthma, inflammation, and cancer
Franck Mauvais-Jarvis, MD, PhD Estrogen and androgen actions in diabetes and obesity
William A. Muller, MD, PhD Leukocyte-endothelial cell interactions in inflammation
Harris Perlman, PhD The role of cell cycle and apoptosis regulators in autoimmune disease
Robert Schleimer, PhD Glucocorticoids in allergic diseases
Paul Schumacker, PhD Oxygen sensing and hypoxia in lung disease and tumor angiogenesis
Christian Stehlik, PhD Molecular mechanisms of inflammatory and infectious disease
Warren G. Tourtellotte, MD, PhD Intracellular signal transduction pathways mediated by immediate early genes
John Varga, MD TGF-ß and the Pathogenesis of Fibrosis
Douglas E. Vaughan, MD Plasminogen activator system in cardiovascular disease
Teresa Woodruff, PhD Ovarian Follicle Growth during the Mammalian Reproductive Cycles
    Development and Morphogenesis
Sara Ahlgren, PhD Craniofacial growth and development
Raj Awatramani, PhD Cell fate specification in the mammalian CNS
Andrea Dunaif, MD Genetic and molecular basis of Polycystic ovary syndrome (PCOS)
Anjen Chenn, MD, PhD Regulation of Cell Fate and Proliferation in Mammalian CNS
Rex Chisholm, PhD Cell motility; cell movement during morphogenesis; myosin; dynein; molecular motors and disease
Christine DiDonato, PhD Molecular basis of spinal muscular atrophy (SMA)
Yuanyi Feng, MD, PhD Mouse models of human genetic diseases
John A. Kessler, MD Stem cell biology and regenerative neuroscience
Hiroaki Kiyokawa, MD, PhD Roles of cell cycle-regulatory proteins in differentiation, senescence and apoptosis
Thomas McGarry, MD, PhD Unstable regulatory proteins and nuclear reprogramming
Jill Morris, PhD Molecular basis of schizophrenia
Puneet Opal, PhD Cellular basis of neurodegeneration
P. Hande Ozdinler, PhD Cell survival, directed differentiation, maturation and axon outgrowth in corticospinal motor neurons
Christopher Payne, PhD Gene regulation in the male germline stem cell
Carol Podlasek, PhD Sonic hedgehog (SHH) signaling in penile development and erectile dysfunction
Teepu Siddique, MD Molecular basis of neurodegeneration and ALS
Hans-Georg Simon, PhD Development and regenerative repair of vertebrate limbs and heart
Jacek Topczewski, PhD Morphogenic processes in zebrafish development
Warren G. Tourtellotte, MD, PhD immediate early gene function during mammalian development
Margrit Urbanek, PhD Susceptibility genes for complex diseases
Olga Volpert, PhD Mechanism of angiogenesis inhibitors
Eugene Xu, PhD Regulators of germ cell development in Drosophila and mice
Ming Zhang, PhD Molecular mechanisms of tumorigenesis and cancer metastasis

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