CANCER BIOLOGY

Faculty Research Interests

  
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    Cell adhesion and motility in organogenesis and angiogenesis
Raymond Bergan, MD Therapeutic modulation of adhesion and motility in human prostate cells
Rex Chisholm, PhD Cell motility; cell movement during morphogenesis; myosin; dynein; molecular motors and disease
Vladimir Gelfand, PhD Cytoskeleton, microtubules, and intracellular transport
Robert Goldman, PhD Cell motility; structure and function of cytoplasmic filament systems
Cara Gottardi, PhD Roles for catenins and cadherins in cell adhesion
Kathleen Green, PhD Intercellular adhesion molecules: junctional and nuclear function and assembly
Sui Huang, PhD Function of perinucleolar compartment in cancer cells
Jonathan Jones, PhD Functional analyses of cell-matrix interactions
Geoffrey Kansas, PhD Molecular biology of leukocyte adhesion and migration
Hidayatullah Munshi, MD Matrix metalloproteinases (MMPs) in metastasizing tumor cells
H. William Schnaper, MD Cell signal transduction in atherosclerosis and fibrogenesis
Ming Zhang, PhD Molecular mechanisms of tumorigenesis and cancer metastasis
    Viral genes and their influence on cellular proliferation and function
Lou Laimins, PhD Human papillomaviruses and cervical cancer
Richard Longnecker, PhD Epstein-Barr virus transformation, latency, and entry
    Regulation of signal transduction pathways
Terry Barrett, MD Beta catenin signaling in intestinal stem cells
Markus Bredel, MD, PhD Human Brain Tumors: Unraveling Disease and Resistance Biology
Irina V. Budunova, MD, PhD Cell signaling and intercellular communications in skin tumorigenesis and development
Serdar Bulun, MD Estrogen metabolism in breast cancer, endometriosis, and uterine fibroids
Anjen Chenn, MD, PhD Regulation of Cell Fate and Proliferation in Mammalian CNS
Charles Clevenger, MD, PhD Molecular endocrinology of the prolactin receptor in breast cancer
Vincent Cryns, MD Caspase Signaling in Apoptosis
Ann Harris, PhD Regulation of CFTR gene expression; mucin glycobiology
Xiaolin He, PhD Structural mechanisms of transmembrane signaling events in cancer
Philip Iannaccone, Md, PhD Tumor clonality; preimplantation; reproductive toxicity
J. Larry Jameson, MD, PhD Genetic basis of endocrine disorders
Jacqueline S. Jeruss, MD, PhD Signaling in Breast Cancer: Disease Development and Progression
William Karpus, PhD The role of chemokines and cytokines in autoimmunity
Khashayarsha Khazaie, PhD, DSc Immune Evasion and Inflammation in Cancer
Michael Klüppel, PhD Chondroitin sulfate in growth factor signaling, development and cancer
Nick Lu, PhD Glucocorticoid receptor in asthma, inflammation, and cancer
Puneet Opal, MD, PhD Cellular basis of neurodegeneration
Jill C. Pelling, PhD Chemoprevention; signal transduction in UV response; hypoxia in carcinogenesis
Boris Pasche, MD, PhD Transforming Growth Factor Beta (TGF-b) in Cancer Development and Progression
Leonidas Platanias, MD, PhD Signal transduction in malignant cells
Steven Rosen, MD Biologic therapies of cancer
Paul Stein, PhD Src family kinases in lymphoid cell development and epithelial cell differentiation
Linda Van Eldik, PhD Brain inflammation, molecular glial biology, and neurodegenerative disorders
Olga Volpert, PhD Mechanism of angiogenesis inhibitors
D. Martin Watterson, PhD Signal Transduction, Chemical Biology and Drug Discovery
    Regulation of gene expression in normal and malignant cells
Vimla Band, PhD Early steps in human breast and cervical cancer
Navdeep Chandel, PhD Tumor Cell Responses to Oxygen Deprivation
Chonghui Cheng, MD, PhD Alternative splicing in cancer development
John Crispino, PhD Transcriptional regulation of normal and malignant blood cell development
Elizabeth Eklund, MD Molecular biology of late myeloid differentiation
J. Julie Kim, PhD Molecular events in the endometrium during early pregnancy, endometriosis and endometrial cancer
Hiroaki Kiyokawa, MD, PhD Roles of cell cycle-regulatory proteins in differentiation, senescence and apoptosis
Chung Lee, PhD Novel approaches to gene therapy in cancer cells
Jonathan Licht, MD Transcription factors disrupted in human cancer - Mechanism of action and targets
Thomas McGarry, MD, PhD Unstable regulatory proteins
Alex Minella, MD Cell cycle control mechanisms in cancer
Toru Ouchi, PhD Mechanism of Human Cancer Development
Janardan Reddy, MD Molecular mechanisms of peroxisome nuclear receptor co-activators
Anthony J. Schaeffer, MD Anti-neoplastic effects of polyamine Inhibitors
Paul Schumacker, PhD Oxygen sensing and hypoxia in tumor angiogenesis
Hank Seifert, PhD Mechanisms of gene recombination in bacteria
Marcelo Soares, PhD Genomic instability, aberrant transcription and splicing in cancer
Warren Tourtellotte, MD, PhD Immediate early gene regulation and oncogenesis
David Walterhouse, MD Function and Regulation of the Oncogene GLI
Susan Winandy, Ph.D. Transcriptional Regulation of T-cell Development

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