GCRC Core Resources

Biostatistical Support

Biostatistician Borko D. Jovanovic, PhD, provides biostatistical support for the GCRC and is available for consultation at all stages of development of the study, including preparation of the protocol prior to submission to the Scientific Advisory Committee (SAC). He is available to provide analysis of data from the study once it is available to the investigator. Dr. Jovanovic reviews all protocols submitted to the SAC.

Dr. Jovanovic holds a BS degree in statistics, an MS degree in applied mathematics, and a PhD degree in biostatistics. In 1991 he received his PhD degree from the School of Public Health, University of Massachusetts at Amherst, focusing his dissertation on efficient variable selection in generalized linear models. Dr. Jovanovic has taught mathematics and statistics at Northeastern University in Boston (1980-1982), University of Massachusetts at Amherst (1982-1989), and University of Illinois at Chicago (1989-1999).

Since 1985 he has worked in various capacities as a statistical consultant and served as a reviewer for medical and health science journals such as JAMA, and Statistics in Medicine and Biometrics. He is a member of the Biometric Society and the American Statistical Association (ASA).

Dr. Jovanovic has research interests in categorical data analysis, clinical trials, rare events, meta-analysis, and statistical analysis of micro-array data in genetics. He divides his time equally between the GCRC, where he is a member of the SAC, and the Robert H. Lurie Comprehensive Cancer Center, where he serves on the Clinical Protocol Scientific Review Monitoring Committee. He works closely with the Informatics Core Manager.

For more information, contact

Borko D. Jovanovic, PhD
GCRC Biostatistician
The Feinberg School of Medicine
Department of Preventive Medicine
680 Lake Shore Drive, Suite 1102
Chicago, IL 60611

Telephone 312/503-2008
Fax 312/908-9588
borko@northwestern.edu

Recommended Biostatistics Links

Association of GCRC Statisticians

American Statistical Association

Statistics info for all

For more links to statistical resources, click here.

Some Recent Publications

 Eklund J, Kozloff M, Vlamakis J, Starr A, Mariott M, Gallot L, Jovanovic B, Schilder L, Robin E, Pins M, Bergan RC. Phase II study of mitoxantrone and ketoconazole for hormone-refractory prostate cancer. Cancer. 2006 Jun 1;106(11):2459-65.
 
 Zhang Q, Zhou W, Kundu S, Jang TL, Yang X, Pins M, Smith N, Jovanovic B, Xin D, Liang L, Guo Y, Lee C.The leader sequence triggers and enhances several functions of clusterin and is instrumental in the progression of human prostate cancer in vivo and in vitro. BJU Int. 2006 Aug;98(2):452-60.
 
 Yvonne Loh, Yu Oyama, Laisvyde Statkute, Kathleen Quigley, Kimberly Yaung, Elizabeth Gonda, Walter Barr, Borko Jovanovic, Robert Craig, Dusan Stefoski, Bruce Cohen, and Richard K Burt. Development of a secondary autoimmune disorder after hematopoietic stem cell transplantation for autoimmune diseases: role of conditioning regimen used? Blood, Nov 2006; doi:10.1182/blood-2006-07-035766.
 
 Y Ding, L Xu, S Chen, B D Jovanovic, I B Helenowski, D L Kelly, W J Catalona, X J Yang, M Pins, V Ananthanarayanan, R C Bergan. Characterization of a method for profiling gene expression in cells recovered from intact human prostate tissue using RNA linear amplification. Prostate Cancer Prostatic Dis. 2006;9(4):379-91.
 
 Borko D. Jovanovic, Yongzeng Ding,  Irene B. Helnowski and Raymond C. Bergan: Northern Blot, PCR and Microarray: Comparing Gene Expression Data. 2006 Proceedings of the American Statistical Association, paper # 818. [CD-ROM]. Alexandria, VA USA 2006.
 
 Synenki L, Chandel NS, Budinger GR, Donnelly HK, Eisenbart J, Jovanovic B, Jain M: Bronchoalveolar lavage fluid from patients with acute lung injury/acute respiratory distress syndrome induces myofibroblast differentiation.Crit Care Med. 2007 Mar;35(3):842-8.
 
 Wendy J. Brickman, Helen J. Binns, Borko D. Jovanovic, Scott Kolesky, Anthony J. Mancini,  Boyd E. Metzger, for the Pediatric Practice Research Group: The Prevalence of Acanthosis Nigricans in African American, Hispanic, and Caucasian Youth Encountered in Pediatric Practice. Nov/Dec 2007;  Pediatric Dermatology

 Naidech AM, Jovanovic B, Wartenberg KE, Parra A, Ostapkovich N, Connolly ES, Mayer SA, Commichau C. Higher hemoglobin is associated with improved outcome after subarachnoid hemorrhage. Crit Care Med 2007 Aug 21.
 
 Yongzeng Ding, Li Xu, Borko Jovanovic, Irene B. Helenowski, David L. Kelly, William J. Catalona, Ximing J. Yang, Michael Pins, and Raymond C. Bergan.  The methodology used to measure differential gene expression affects the outcome, The Journal of Biomolecular Techniques, In Press 2007
 
  Norvell JP, Blei AT, Jovanovic BD , Levitsky J.: Herpes simplex virus hepatitis: An analysis of the published literature and institutional cases. Liver Transpl. 2007 Oct;13(10):1428-34. PMID: 17902129
 
 Jain M, Upadhyay D, Balagani R, Jovanovic B, Fintel D. Cardiologists use pulmonary artery catheter information to make homogenous treatment decisions. J Intensive Care Med. 2007 Sep-Oct;22(5):251-6.
 
Oyama Y, Barr WG, Statkute L, Corbridge T, Gonda EA, Jovanovic B, Testori A, Burt RK. Autologous non-myeloablative hematopoietic stem cell transplantation in patients with systemic sclerosis. Bone Marrow Transplant. 2007 Sep;40(6):549-55.