John D Crispino, PhD

John D Crispino, PhD

Robert I. Lurie, MD, and Lora S. Lurie Professor

Professor of Medicine (Hematology and Oncology) and Biochemistry and Molecular Genetics



Robert H Lurie Medical Research Center Room 5-250
303 E Superior
Chicago IL 60611

Education and Certification

PhD: MIT, Biology (1996)


Description of Interests

Research in the Crispino laboratory is focused on investigating the regulatory mechanisms governing normal and malignant blood cell development, with an emphasis on understanding the growth of erythroid cells (red blood cells) and megakaryocytes (platelet-producing cells). In addition, the group has a major interest in learning how changes in normal essential regulatory molecules lead to human blood diseases, including acute leukemias and myeloproliferative neoplasms (MPNs). The lab seeks to make seminal basic science discoveries while simultaneously translating these discoveries in ways that will benefit patients with hematologic malignancies.

Interests (Keywords)

Blood/Bleeding Disorders (anemia, clotting, etc.); Cancer: Blood (leukemia, lymphomas); Gene Regulation; Molecular Biology

Research and Publications

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