Northwestern University Feinberg School of Medicine
Faculty Profiles

Focus of Work

Bio

Stem Cell Transplantation for Pediatric diseases Minimal residual disease in leukemia Neuroblastoma and its treatment Stem Cell differentiation Tumor vaccines.

Academic Focus

I have been involved in Clinical research for Neuroblastoma and stem cell transplantation. I have also for the past 26 year have a laboratory that was focused on several projects such as:
1. Minimal Residual Disease in leukemia and neuroblastoma using WT1 gene as a marker.
2. Hematopoietic stem cell differentiation primarily on neural differentiation.
3. The use of RT-PCR to assess chimerism post transplant.
4. Stem cell processing and storage.
5. neuroblastoma tumor stem cell identificati...[Read full text]
I have been involved in Clinical research for Neuroblastoma and stem cell transplantation. I have also for the past 26 year have a laboratory that was focused on several projects such as:
1. Minimal Residual Disease in leukemia and neuroblastoma using WT1 gene as a marker.
2. Hematopoietic stem cell differentiation primarily on neural differentiation.
3. The use of RT-PCR to assess chimerism post transplant.
4. Stem cell processing and storage.
5. neuroblastoma tumor stem cell identification and its role in disease development.[Shorten text]

Clinical Focus

My clinical focus has been related to Hematopoietic Stem Cell transplantation both autologous and allogeneic. I have also developed and participate at the national level in the development of therapeutic protocols for neuroblastoma , leukemia and lymphoma at the former Pediatric Oncology group and the Children's Oncology Group.
Most recently I have been the Institutional PI for the Pediatric Immune Deficiency consortium developing protocols for the transplant of patients affected with immune def...[Read full text]
My clinical focus has been related to Hematopoietic Stem Cell transplantation both autologous and allogeneic. I have also developed and participate at the national level in the development of therapeutic protocols for neuroblastoma , leukemia and lymphoma at the former Pediatric Oncology group and the Children's Oncology Group.
Most recently I have been the Institutional PI for the Pediatric Immune Deficiency consortium developing protocols for the transplant of patients affected with immune deficiency disorders.[Shorten text]

Keywords


Education and Certification

  • MD: Facultad de Medicina de la UNAM (1971)
  • Internship: University of Tel Aviv, Pediatrics (1972)
  • Residency: University of Arkansas Hospital, Pediatrics (1977)
  • Fellowship: University of Texas/MD Anderson Cancer Center, Hematology/Oncology (1980)
  • Board Certification: Pediatric Hematology-Oncology, Pediatrics