Fall 2009

Biostatistics Collaboration Center Lecture Series
Biostatistics in Medical Research

The Biostatistics Collaboration Center (BCC) in the Northwestern University Feinberg School of Medicine will be offering a series of 6 free introductory lectures on biostatistics in medical research.  The lectures will be non-technical and have been designed with the following objectives:

• To assist participants in interpreting statistics published in the medical literature.
• To highlight different statistical methodology for investigators considering their own research.
• To facilitate the communication between medical researchers and biostatisticians.

The lectures are FREE and open to interested members of the Northwestern community!  Click here to download flyer.  Registration is NOT required.  Seating is available on first come basis.  Lectures are 1 hour in length followed by 30 mins of Q&A.  Lecture slides will be available to view and download one week prior to each lecture.

All lectures will be held in Daniel Hale Williams Auditorium (McGaw 2-320) at 240 East Huron from 12:30-1:30pm.

Thursday, October 1^st 12:30 – 1:30 PM
#1 – Basic Concepts     Download Presentation! (pdf)

• Data types and corresponding summary statistics
• One sample inference

Thursday, October 8^th 12:30 – 1:30 PM
#2 – Two Group Comparisons     Download Presentation! (pdf)

• Two sample tests (parametric and nonparametric tests)

Thursday, October 15^th 12:30 – 1:30 PM
#3 – Introduction to Linear Regression and Logistic Regression    Download Presentation! (pdf)

• Simple linear regression
• Multiple linear regression
  -  estimating parameter
  -  testing hypotheses about parameters
  -  confidence and prediction interval
• Logistic regression
  -  odds ratio vs. relative risk
  -  univariate, multiple logistic regression
  -  interpretation of coefficient
  -  extensions of logistic regression

Thursday, October 22^th 12:30 – 1:30 PM
#4 – Statistical Power     Download Presentation! (pdf)

• Importance and limits
• Terminology
• Examples 

Thursday, October 29^th 12:30 – 1:30 PM
#5 – Analysis of Time to Event (Survival) Data    Download Presentation! (pdf)  

• Terminology
• Comparing Survivorship
• Regression Models  

Thursday, November 5^th 12:30 – 1:30 PM
#6 – Introduction to Statistics in Genetics Research   Download Presentation! (pdf)  

• Statistical methods for dichotomous traits
  -  Linkage analysis
  -  LOD score
  -  Genome-wide association (GWA) studies
• Statistical methods for quantitative traits
  -  Quantitative Trait Loci (QTL) analysis
  -  Expression QTL (eQTL) analysis