Palmer, L.S., Lee, C., Decker, R.S., Lang, S., Kaplan, W.E., Firlit, C.F., and Cheng, E.Y.: The effect of angiotensin converting enzyme inhibition and angiotensin II receptor antagonism on the obstructed rat bladder. J. Urol., 158:1100, 1997.
Cheng, E.Y., Lee, C., and Decker, R.S. Role of angiotensin II in bladder smooth muscle growth and function . Adv. Exp. Med. Biol., 462: 183-191, 1999.
Furness, P.D., Maizels, M., Han, S.W., Cohn, R.A., and Cheng, E.Y.: Elevated bladder urine concentration of transforming growth factor-beta 1 correlates with upper urinary tract obstruction in children. J.Urol., 162: 1033, 1999.
Kropp, B.P., Zhang, Y.Y., Tomasek, J.J., Cowan, R., Furness, P.D., Vaughan, M.B., Parizi, M., and Cheng, E.Y.: Characterization of cultured bladder smooth muscle cells: assessment of in vitro contractility. J.Urol., 162: 1179, 1999.
Cheng, E.Y. Cellular factors and the obstructed bladder. J. Urol., 164(4), 1334-5, 2000.
Zhang, Y., Kropp, B.P., Moore P., Cowan, R., Furness, P.D., Kolligian, M.E., Frey P., and Cheng, E.Y. Coculture of bladder urothelial and smooth muscle cells on small intestinal submucosa: potential applications for tissue engineering technology .J. Urol., 164(3 Pt 2), 928-34, discussion 934-5, 2000.
Bankhead, R.W., Kropp, B. P. and Cheng, E.Y. Evaluation and treatment of children with neurogenic bladders. J. Child Neurol., 15(3), 141-9, 2000.
Kropp, B.P. and Cheng. E.Y. Bioengineering organs using small intestinal submucosa scaffolds: in vivo tissue-engineering technology. J. Endourol., 14(1), 59-62, 2000.
Han, S.W., Maizels, M., Chou, P.M., Fernbach, S.K., Cheng, E.Y., and Furness, P.D.: Lamina muscularis propria thickness of renal pelvis predicts radiological outcome of surgical correction of ureteropelvic junction obstruction. J. Urol., 165: 1648, 2001.
Colvert, J.R., Kropp, B.P., Austin, P., Cheng, E.Y., Pope, J.C., Brock, J.W., Adams, M.C., Furness, P.D., and Koyle M.A.: The use of small intestinal submucosa (SIS) as an “off the shelf” urethral sling material for pediatric urinary incontinence. J. Urol., 168(4 Pt 2): 1872, 2002.
Cheng, E.Y., Vemulapalli, S.N., Kropp, B.P., Pope, J.C., Furness, P.D., Kaplan, W.E., and Smith, D.P.: Snodgrass hypospadias repair with vascularized flap: the perfect repair for virgin hypospadias? J. Urol., 168 (4 Pt 2): 1723, 2002.
Beqaj SH, Donovan JL, Liu DB, Harrington DA, Alpert SA, Cheng EY. Role of basic fibroblast growth factor in the neuropathic bladder phenotype. J Urol. (in press) 2005.
Research Support
1R01DK56968-01A1 Kropp (PI) 2000-2005 NIH A Comparison of in vivo and in vitro Tissue Engineering. This study investigates the utility of small intestinal submucosa (SIS) and synthetic scaffolds, both in the seeded and unseeded form, for use in bladder tissue engineering. Role: Co-Investigator
Edwin Beer Program/Fellowship Cheng (PI) 2001-2003 The New York Academy of Medicine Use of Neuropathic Bladder Cells for Tissue Engineering This study investigates the functional differences between cultured neuropathic and normal bladder smooth muscle cells in vitro. Role: Principal Investigator
Children's Memorial Hospital Internal Funding Cheng (PI) 2003-2006 Children’s Memorial Hospital Use of Neuropathic Bladder Cells for Tissue Engineering This study seeks to show that neuropathic bladder smooth muscle cells utilized tissue engineering will retain neuropathic functional properties. Role: Principal Investigator
National Institutes of Health R21 Cheng (PI) 2005-2007 Northwestern University / Children's Memorial Hospital Bladder Tissue Engineering through Nanotechnology This study investigates peptide-amphiphile molecules for the delivery of bFGF and VEGF to regenerating bladder tissue. Role: Principal Investigator
The Cheng Laboratory Northwestern University, Feinberg School of Medicine 303 East Superior Lurie 11-219 Chicago, IL 60611 Phone: 312/503-6104