Craig B. Langman, MD 

Isaac A. Abt, MD Professor of Kidney Diseases
Feinberg School of Medicine, Northwestern University
Head, Kidney Diseases, Children’s Memorial Medical Center                                                                     
Department of Pediatrics
c-langman@northwestern.edu
773-327-3930
www.iccbh4.org

Current Research

• We are interested in genetic and acquired bone diseases of infants, children, and adolescents, and the effects of bone-specific therapy for them. 
• We are interested in the osteodystrophy of chronic kidney disease, as a systemic disorder of bone and the vasculature.
• We are interested in kidney stone diseases, including the primary hyperoxalurias, Dent’s disease, and disorders of the extracellular calcium-sensing receptor. 
• We serve as a resource for measurement of bone and mineral homeostatic factors and agents, such as FGF-23, OPG, RANKL, TGF-β, inflammatory cytokines, and others.

Recent Publications

Langman CB.  Genetic regulation of bone mass: from bone density to bone strength.  Pediatr Nephrol. 2005 Mar;20(3):352-5. Epub 2005 Jan 5.

Langman CB.  Improvement of bone in patients with osteogenesis imperfecta treated with pamidronate-lessons from biochemistry.  J Clin Endocrinol Metab. 2003 Mar;88(3):984-5.

Langman CB.  The molecular basis of kidney stones.  Curr Opin Pediatr. 2004 Apr;16(2):188-93.

Edwards BJ, Brooks ER, Langman CB.  Osteoporosis screening of postmenopausal women in the primary care setting: a case-based approach.  Gend Med. 2004 Dec;1(2):70-85.

Rosenson RS, Tangney CC, Langman CB, Parker TS, Levine DM, Gordon BR.  Short-term reductioidin bone markers with high-dose simvastatin.  Osteoporos Int. 2005 Oct;16(10):1272-6.

Ariceta G, Brooks ER, Langman CB.  Assessing cardiovascular risk in children with chronic kidney disease. B-type natriuretic peptide: a potential new marker.  Pediatr Nephrol. 2005 Dec;20(12):1701-7.
 
Langman CB.  Renal osteodystrophy: a pediatric perspective, 2005.  Growth Horm IGF Res. 2005 Jul;15 Suppl A:42-7.

Adler JL, Backer CL, Langman CB.  Hypertensive emergency associated with thoracoabdominal aneurysm: case report and review.  Pediatr Crit Care Med. 2005 May;6(3):359-62.

Klein GL, Chen TC, Holick MF, Langman CB, Price H, Celis MM, Herndon DN.  Synthesis of vitamin D in skin after burns.  Lancet. 2004 Jan 24;363(9405):291-2.

Ramsey-Goldman R, Schilling EM, Dunlop D, Langman C, Greenland P, Thomas RJ, Chang RW.  A pilot study on the effects of exercise in patients with systemic lupus erythematosus.  Arthritis Care Res. 2000 Oct;13(5):262-9.